Biomedical Elastomeric Polyurethanes Based on Poly(ethylene glycol)

Biomedical Elastomeric Polyurethanes Based on Poly(ethylene glycol)

Abstract

Biodegradable polyurethane (bio-PU) elastomers with potential use as scaffolds in a regenerative medicine were synthesized using poly(ethylene glycol) (PEG), poly(caprolactone) (PCL) and hexamethylene diisocyanate catalyzed with stannous octoate. Effect of bio-PU composition on the swelling and hydrolytic stability was investigated together with testing mechanical properties, monitoring of net formation and the degree of conversion of prepared samples. The morphology of prepared samples was analysed by optical microscopy. Chemical composition was tested by infrared spectroscopy and the thermal properties were measured by differential scanning calorimetry.

Biodegradable polyurethane (bio-PU) elastomers with potential use as scaffolds in a regenerative medicine were synthesized using poly(ethylene glycol) (PEG), poly(caprolactone) (PCL) and hexamethylene diisocyanate catalyzed with stannous octoate. Effect of bio-PU composition on the swelling and hydrolytic stability was investigated together with testing mechanical properties, monitoring of net formation and the degree of conversion of prepared samples. The morphology of prepared samples was analysed by optical microscopy. Chemical composition was tested by infrared spectroscopy and the thermal properties were measured by differential scanning calorimetry.

polyurethane, elastomer, synthesis, poly(ethylene glycol), poly(caprolactone), hexamethylene diisocyanate

polyurethane, elastomer, synthesis, poly(ethylene glycol), poly(caprolactone), hexamethylene diisocyanate

KUPKA, V.; VOJTOVÁ, L.; BÁLKOVÁ, R.; POLÁČEK, P.; SEDLÁČEK, P.; JANČÁŘ, J.

2012

17.08.2011

Česká společnost chemická

Praha

0009-2770

CHEMICKE LISTY

105

18

Czech Republic

s931

s931

1