VISCOELASTIC PROPERTIES OF COLLAGEN

VISCOELASTIC PROPERTIES OF COLLAGEN

Abstract

Proteins are materials with the characteristic hierarchical design, which involves formation of multi-functional and stimuli responsive materials. Collagen is Nature's most abundant structural protein and the basic building unit of human body. There are many types of collagen, but the most abundant is collagen I, which forms almost 90 % of collagen in human body. It is essential in forming bones, skin, tendons, cornea and ligaments. Rheological properties of collagen are significant, because it is widely used as a biomaterial. It is well known that many biological soft tissues behave as viscoelastic materials with hysteresis curves being nearly independent of strain rate when loading frequency is varied over a large range [1]. Influence of structural parameters such as degree of crosslinking, concentration and pH on viscoelastic properties will be assessed in this work.

Proteins are materials with the characteristic hierarchical design, which involves formation of multi-functional and stimuli responsive materials. Collagen is Nature's most abundant structural protein and the basic building unit of human body. There are many types of collagen, but the most abundant is collagen I, which forms almost 90 % of collagen in human body. It is essential in forming bones, skin, tendons, cornea and ligaments. Rheological properties of collagen are significant, because it is widely used as a biomaterial. It is well known that many biological soft tissues behave as viscoelastic materials with hysteresis curves being nearly independent of strain rate when loading frequency is varied over a large range [1]. Influence of structural parameters such as degree of crosslinking, concentration and pH on viscoelastic properties will be assessed in this work.

collagen I, viscoelasticity

collagen I, viscoelasticity

TOMEČKOVÁ, N., JANČÁŘ J.

2012

17.08.2011

0009-2770

CHEMICKE LISTY

105

18

Czech Republic

s940

s940