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DRBOHLAVOVÁ, J.; CHOMOUCKÁ, J.; ADAM, V.; VACULOVIČOVÁ, M.; HUBÁLEK, J.; KIZEK, R.
Original Title
Nanocarriers for anticancer drugs - New trends in nanomedicine
English Title
Type
Peer-reviewed article not indexed in WoS or Scopus
Original Abstract
This review provides a brief overview of the variety of carriers employed for targeted drug delivery used in cancer therapy summarizing advantages and disadvantages of each approach. Particularly, we aim our attention at polymeric nanocarriers, liposomes, micelles, polyethylene glycol, poly(lactic-co-glycolic acid), dendrimers, gold and magnetic nanoparticles, quantum dots, silica nanoparticles and carbon nanotubes. Further, we briefly focus on several anticancer agents (paclitaxel, docetaxel, camptothecin, doxorubicin, daunorubicin, cisplatin, curcumin and geldanamycin) and to the influence of their combination with nanoparticulate transporters to their properties such as cytotoxicity, short life time and/or solubility
English abstract
Keywords
Nanotechnologies; Nanoparticles; Gene Therapy; Anticancer drugs; Drug carriers; Cancer; Cytostatic; Targeted therapy.
Key words in English
Authors
RIV year
2014
Released
13.05.2013
Publisher
Bentham Science
Location
Sharjah, U. A. E.
ISBN
1389-2002
Periodical
CURRENT DRUG METABOLISM
Volume
14
Number
5
State
United Arab Emirates
Pages from
547
Pages to
564
Pages count
18
BibTex
@article{BUT75687, author="Jana {Drbohlavová} and Jana {Pekárková} and Vojtěch {Adam} and Markéta {Vaculovičová} and Jaromír {Hubálek} and René {Kizek}", title="Nanocarriers for anticancer drugs - New trends in nanomedicine", journal="CURRENT DRUG METABOLISM", year="2013", volume="14", number="5", pages="547--564", doi="10.2174/1389200211314050005", issn="1389-2002" }