Detail publikačního výsledku

Fluorescence Spectroscopy Study of Hyaluronan-Phospholipid Interactions

MRAVEC, F.; KLUČÁKOVÁ, M.; PEKAŘ, M.

Original Title

Fluorescence Spectroscopy Study of Hyaluronan-Phospholipid Interactions

English Title

Fluorescence Spectroscopy Study of Hyaluronan-Phospholipid Interactions

Type

Chapter in a book

Original Abstract

Capability of phospholipids with positive charge to form complexes with hyaluronan in aqueous solutions, in a similar way as traditional cationic surfactants, was investigated by fluorescence probes. DPPC and lecithin aggregate in aqueous solution to form micelle-like structures capable to solubilize hydrophobic molecules. Changes in aggregation behavior after adding hyaluronan were observed only in the case of lecithin. Further, non-ionic biocompatible surfactant was used as additional dispersion environment in phospholipid-hyaluronan system with phospholipid molecules acting as a physical linker bonding micelles and biopolymer.

English abstract

Capability of phospholipids with positive charge to form complexes with hyaluronan in aqueous solutions, in a similar way as traditional cationic surfactants, was investigated by fluorescence probes. DPPC and lecithin aggregate in aqueous solution to form micelle-like structures capable to solubilize hydrophobic molecules. Changes in aggregation behavior after adding hyaluronan were observed only in the case of lecithin. Further, non-ionic biocompatible surfactant was used as additional dispersion environment in phospholipid-hyaluronan system with phospholipid molecules acting as a physical linker bonding micelles and biopolymer.

Keywords

fluorescence probe, hyaluronan, interactions, phospholipid

Key words in English

fluorescence probe, hyaluronan, interactions, phospholipid

Authors

MRAVEC, F.; KLUČÁKOVÁ, M.; PEKAŘ, M.

RIV year

2012

Released

01.10.2011

Publisher

Academic Press

Location

Burlington

ISBN

978-0-12-387720-8

Book

Advances in Planar Lipid Bilayers and Liposomes

Edition

není

Pages from

235

Pages to

255

Pages count

21

Full text in the Digital Library

http://hdl.handle.net/

BibTex

@inbook{BUT74322,
  author="Filip {Mravec} and Martina {Klučáková} and Miloslav {Pekař}",
  title="Fluorescence Spectroscopy Study of Hyaluronan-Phospholipid Interactions",
  booktitle="Advances in Planar Lipid Bilayers and Liposomes",
  year="2011",
  publisher="Academic Press",
  address="Burlington",
  series="není",
  edition="14",
  pages="235--255",
  isbn="978-0-12-387720-8"
}