Publication result detail

Aggregation behavior of novel hyaluronan derivatives-a fluorescence probe study

MRAVEC, F.; PEKAŘ, M.; VELEBNÝ, V.

Original Title

Aggregation behavior of novel hyaluronan derivatives-a fluorescence probe study

English Title

Aggregation behavior of novel hyaluronan derivatives-a fluorescence probe study

Type

Peer-reviewed article not indexed in WoS or Scopus

Original Abstract

Aggregation properties of hydrophobized hyaluronan (hHA) in different molecular weights and degree of substitution were studied by pyrene and perylene fluorescence method. The critical aggregation concentration (cac) was determined by the pyrene I1/I3 and perylene fluorescence intensity method. The value of the cac for the hHA in aqueous solution was measured at different molecular weights and at 293.2 K. The cac value varied both with the molecular weight and the degree of substitution and was between 0.610-0.003 g L?1. Pyrene Polarity Scale confirmed formation of hydrophobic domains of the relative hydrophobic index about 0.85.

English abstract

Aggregation properties of hydrophobized hyaluronan (hHA) in different molecular weights and degree of substitution were studied by pyrene and perylene fluorescence method. The critical aggregation concentration (cac) was determined by the pyrene I1/I3 and perylene fluorescence intensity method. The value of the cac for the hHA in aqueous solution was measured at different molecular weights and at 293.2 K. The cac value varied both with the molecular weight and the degree of substitution and was between 0.610-0.003 g L?1. Pyrene Polarity Scale confirmed formation of hydrophobic domains of the relative hydrophobic index about 0.85.

Keywords

hyaluronate derivatives - fluorescence probes - critical aggregation concentration - core hydrophobicity

Key words in English

hyaluronate derivatives - fluorescence probes - critical aggregation concentration - core hydrophobicity

Authors

MRAVEC, F.; PEKAŘ, M.; VELEBNÝ, V.

RIV year

2010

Released

01.11.2008

Publisher

Springer-Verlag

ISBN

0303-402X

Periodical

COLLOID AND POLYMER SCIENCE

Volume

286

Number

14-15

State

Federal Republic of Germany

Pages from

1681

Pages to

1685

Pages count

5

URL

http://link.springer.com/article/10.1007/s00396-008-1941-8/fulltext.html

Full text in the Digital Library

http://hdl.handle.net/11012/19702

BibTex

@article{BUT47579,
  author="Filip {Mravec} and Miloslav {Pekař} and Vladimír {Velebný}",
  title="Aggregation behavior of novel hyaluronan derivatives-a fluorescence probe study",
  journal="COLLOID AND POLYMER SCIENCE",
  year="2008",
  volume="286",
  number="14-15",
  pages="1681--1685",
  doi="10.1007/s00396-008-1941-8",
  issn="0303-402X",
  url="http://link.springer.com/article/10.1007/s00396-008-1941-8/fulltext.html"
}

Documents

Aggregation behavior of novel hyaluronan