Publication result detail

Proteomics-on-a-Chip - Microfluidics meets proteomics

ZHANG, H.; ZHAO, L.; BRODSKÝ, J.; MIGLIACCIO, L.; GABLECH, I.; NEUŽIL, P.; YOU, M.

Original Title

Proteomics-on-a-Chip - Microfluidics meets proteomics

English Title

Proteomics-on-a-Chip - Microfluidics meets proteomics

Type

WoS Article

Original Abstract

Proteomics provides an understanding of biological systems by enabling the detailed study of protein expression profiles, which is crucial for early disease diagnosis. Microfluidic-based proteomics enhances this field by integrating complex proteome analysis into compact and efficient systems. This review focuses on developing microfluidic chip structures for proteomics, covering on-chip sample pretreatment, protein extraction, purification, and identification in recent years. Furthermore, our work aims to inspire researchers to select proper methodologies in designing novel, efficient assays for proteomics applications by analyzing trends and innovations in this field.

English abstract

Proteomics provides an understanding of biological systems by enabling the detailed study of protein expression profiles, which is crucial for early disease diagnosis. Microfluidic-based proteomics enhances this field by integrating complex proteome analysis into compact and efficient systems. This review focuses on developing microfluidic chip structures for proteomics, covering on-chip sample pretreatment, protein extraction, purification, and identification in recent years. Furthermore, our work aims to inspire researchers to select proper methodologies in designing novel, efficient assays for proteomics applications by analyzing trends and innovations in this field.

Keywords

Proteomics; Microfluidics; Lab-on-chip

Key words in English

Proteomics; Microfluidics; Lab-on-chip

Authors

ZHANG, H.; ZHAO, L.; BRODSKÝ, J.; MIGLIACCIO, L.; GABLECH, I.; NEUŽIL, P.; YOU, M.

Released

01.04.2025

Publisher

ELSEVIER ADVANCED TECHNOLOGY

Location

NETHERLANDS

ISBN

0956-5663

Periodical

BIOSENSORS & BIOELECTRONICS

Volume

273

Number

4

State

Kingdom of the Netherlands

Pages from

1

Pages to

17

Pages count

17

URL

https://www.sciencedirect.com/science/article/pii/S0956566324011291?via=ihub

BibTex

@article{BUT197011,
  author="ZHANG, H. and ZHAO, L. and BRODSKÝ, J. and MIGLIACCIO, L. and GABLECH, I. and NEUŽIL, P. and YOU, M.",
  title="Proteomics-on-a-Chip - Microfluidics meets proteomics",
  journal="BIOSENSORS & BIOELECTRONICS",
  year="2025",
  volume="273",
  number="4",
  pages="1--17",
  doi="10.1016/j.bios.2024.117122",
  issn="0956-5663",
  url="https://www.sciencedirect.com/science/article/pii/S0956566324011291?via=ihub"
}