Detail publikačního výsledku

Deposition of rigid glass fibres inside a replica of female airways

KÁNSKÁ, J.; LÍZAL, F.; BĚLKA, M.

Original Title

Deposition of rigid glass fibres inside a replica of female airways

English Title

Deposition of rigid glass fibres inside a replica of female airways

Type

Paper in proceedings outside WoS and Scopus

Original Abstract

Inhaled fibrous microparticles can pose serious health risks, which have led to significant attention in the last decades. Fibres, particularly the smaller ones, can penetrate deeply into the lungs and reach the alveoli. Their elongated shape causes this. Usual inhalable spherical drugs in the size range of 5 – 10 µm have difficulty reaching the deeper regions of the lung. Thus, the fibrous shape may provide a solution for delivery in these regions, but the mechanics of inhaled fibre flow are more complex compared to spherical particles. Therefore, it is important to understand how specific parameters (e.g. breathing flowrate, dimensions of fibres) influence the flow and deposition of fibrous aerosols in the human airways.

English abstract

Inhaled fibrous microparticles can pose serious health risks, which have led to significant attention in the last decades. Fibres, particularly the smaller ones, can penetrate deeply into the lungs and reach the alveoli. Their elongated shape causes this. Usual inhalable spherical drugs in the size range of 5 – 10 µm have difficulty reaching the deeper regions of the lung. Thus, the fibrous shape may provide a solution for delivery in these regions, but the mechanics of inhaled fibre flow are more complex compared to spherical particles. Therefore, it is important to understand how specific parameters (e.g. breathing flowrate, dimensions of fibres) influence the flow and deposition of fibrous aerosols in the human airways.

Keywords

fibres;fibers;glass;female airways;inhalation

Key words in English

fibres;fibers;glass;female airways;inhalation

Authors

KÁNSKÁ, J.; LÍZAL, F.; BĚLKA, M.

RIV year

2025

Released

11.11.2024

Publisher

Czech Aerosol Society

Location

Milovy - Sněžné

ISBN

978-80-908653-2-7

Book

PROCEEDINGS of the 23rd Annual Conference of the Czech Aerosol Society OVZDUŠÍ V ČASe

Pages count

2

URL

http://cas.icpf.cas.cz/download/Sbornik_VKCAS_2024.pdf

Full text in the Digital Library

http://hdl.handle.net/

BibTex

@inproceedings{BUT196427,
  author="Jana {Kánská} and František {Lízal} and Miloslav {Bělka}",
  title="Deposition of rigid glass fibres inside a replica of female airways",
  booktitle="PROCEEDINGS of the 23rd Annual Conference of the Czech Aerosol Society OVZDUŠÍ V ČASe",
  year="2024",
  pages="2",
  publisher="Czech Aerosol Society",
  address="Milovy - Sněžné",
  isbn="978-80-908653-2-7",
  url="http://cas.icpf.cas.cz/download/Sbornik_VKCAS_2024.pdf"
}