Publication result detail

ANALYSIS OF RELATIONSHIPS BETWEEN HETEROGENUOUS RADIOMIC FEATURES OF THROMBUS IN ACUTE ISCHEMIC STROKE

NEMČEKOVÁ, P.; ŠKRVÁŇ, A.; MARQUERING, H.; CHMELÍK, J.; JAKUBÍČEK, R.

Original Title

ANALYSIS OF RELATIONSHIPS BETWEEN HETEROGENUOUS RADIOMIC FEATURES OF THROMBUS IN ACUTE ISCHEMIC STROKE

English Title

ANALYSIS OF RELATIONSHIPS BETWEEN HETEROGENUOUS RADIOMIC FEATURES OF THROMBUS IN ACUTE ISCHEMIC STROKE

Type

Scopus Article

Original Abstract

Ischemic stroke is one of the most widely recognised cerebral pathologies. Its diagnosis starts with computed tomography (CT). However, a comprehensive understanding of the characteristics of the thrombus is necessary to establish an appropriate and less hazardous treatment. This study focusses on the analysis of thrombus heterogeneity in CT images of patients with acute ischemic stroke (AIS). The radiomic features of the thrombus were used to obtain the voxel distribution in the new feature space. It was then reduced using PCA and subjected to visualisation techniques such as t-distributed Stochastic Neighbour Embedding (tSNE) and UMAP. By evaluating the morphological structure of the clusters created within patients, it was possible to determine the number of thrombus components. This information could help the physician predict the burden on the patient during thrombectomy, such as the number of attempts required for recanalisation.

English abstract

Ischemic stroke is one of the most widely recognised cerebral pathologies. Its diagnosis starts with computed tomography (CT). However, a comprehensive understanding of the characteristics of the thrombus is necessary to establish an appropriate and less hazardous treatment. This study focusses on the analysis of thrombus heterogeneity in CT images of patients with acute ischemic stroke (AIS). The radiomic features of the thrombus were used to obtain the voxel distribution in the new feature space. It was then reduced using PCA and subjected to visualisation techniques such as t-distributed Stochastic Neighbour Embedding (tSNE) and UMAP. By evaluating the morphological structure of the clusters created within patients, it was possible to determine the number of thrombus components. This information could help the physician predict the burden on the patient during thrombectomy, such as the number of attempts required for recanalisation.

Keywords

ischemic stroke; thrombus; radiomics; heterogeneity; computed tomography

Key words in English

ischemic stroke; thrombus; radiomics; heterogeneity; computed tomography

Authors

NEMČEKOVÁ, P.; ŠKRVÁŇ, A.; MARQUERING, H.; CHMELÍK, J.; JAKUBÍČEK, R.

RIV year

2025

Released

31.12.2023

Publisher

Czech Medical Association J.E. Purkyne

ISBN

0301-5491

Periodical

Lékař a technika

Volume

53

Number

2

State

Czech Republic

Pages from

37

Pages to

41

Pages count

5

URL

https://ojs.cvut.cz/ojs/index.php/CTJ/article/view/9453/7159

BibTex

@article{BUT188008,
  author="Petra {Nemčeková} and Adam {Škrváň} and Henk {Marquering} and Jiří {Chmelík} and Roman {Jakubíček}",
  title="ANALYSIS OF RELATIONSHIPS BETWEEN HETEROGENUOUS RADIOMIC FEATURES OF THROMBUS IN ACUTE ISCHEMIC STROKE",
  journal="Lékař a technika",
  year="2023",
  volume="53",
  number="2",
  pages="37--41",
  doi="10.14311/CTJ.2023.2.01",
  issn="0301-5491",
  url="https://ojs.cvut.cz/ojs/index.php/CTJ/article/view/9453/7159"
}

Documents

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