Publication result detail

Engineered magnetic plant biobots for nerve agent removal

SONG, S.; MAYORGA-MARTINEZ, C.; HÚSKA, D.; PUMERA, M.

Original Title

Engineered magnetic plant biobots for nerve agent removal

English Title

Engineered magnetic plant biobots for nerve agent removal

Type

WoS Article

Original Abstract

Biohybrid micro/nanorobots that integrate biological entities with artificial nanomaterials have shown great potential in the field of biotechnology. However, commonly used physical hybridization approaches can lead to blockages and damage to biological interfaces, impeding the optimal exploitation of natural abilities. Here, we show that magnetically propelled plant biobots (MPBs), employing tomato-callus cultivation engineering in the presence of Fe3O4 nanoparticles (NPs), are capable of active movement and directional guidance under a transversal rotating magnetic field. The Fe3O4 NPs were transported through the cell growth media and then taken up into the plant tissue cells (PTCs), imparting the plant biobot with magnetic function. Moreover, Fe ions support the growth of callus cells, resulting in nanoparticle incorporation and enabling faster growth and structurally compact texture. The magnetic plant biobots demonstrated rapid and efficient removal of chlorpyrifos (approximately 80%), a hazardous nerve gas agent that causes severe acute toxicity, and recovery using an external magnetic field. The eco-friendly plant biobots described here demonstrate their potential in biomedical and environmental applications.

English abstract

Biohybrid micro/nanorobots that integrate biological entities with artificial nanomaterials have shown great potential in the field of biotechnology. However, commonly used physical hybridization approaches can lead to blockages and damage to biological interfaces, impeding the optimal exploitation of natural abilities. Here, we show that magnetically propelled plant biobots (MPBs), employing tomato-callus cultivation engineering in the presence of Fe3O4 nanoparticles (NPs), are capable of active movement and directional guidance under a transversal rotating magnetic field. The Fe3O4 NPs were transported through the cell growth media and then taken up into the plant tissue cells (PTCs), imparting the plant biobot with magnetic function. Moreover, Fe ions support the growth of callus cells, resulting in nanoparticle incorporation and enabling faster growth and structurally compact texture. The magnetic plant biobots demonstrated rapid and efficient removal of chlorpyrifos (approximately 80%), a hazardous nerve gas agent that causes severe acute toxicity, and recovery using an external magnetic field. The eco-friendly plant biobots described here demonstrate their potential in biomedical and environmental applications.

Keywords

PESTICIDES; GROWTH; TRANSLOCATION; NANOPARTICLES; IMPACT; CHLORPYRIFOS; MICROMOTORS; RESPONSES; ACID

Key words in English

PESTICIDES; GROWTH; TRANSLOCATION; NANOPARTICLES; IMPACT; CHLORPYRIFOS; MICROMOTORS; RESPONSES; ACID

Authors

SONG, S.; MAYORGA-MARTINEZ, C.; HÚSKA, D.; PUMERA, M.

RIV year

2023

Released

01.12.2022

Publisher

NATURE PORTFOLIO

Location

BERLIN

ISBN

1884-4057

Periodical

NPG Asia Materials

Volume

14

Number

1

State

Japan

Pages count

10

URL

https://www.nature.com/articles/s41427-022-00425-0

BibTex

@article{BUT182304,
  author="Su-Jin {Song} and Carmen C. {Mayorga-Martinez} and Dalibor {Húska} and Martin {Pumera}",
  title="Engineered magnetic plant biobots for nerve agent removal",
  journal="NPG Asia Materials",
  year="2022",
  volume="14",
  number="1",
  pages="10",
  doi="10.1038/s41427-022-00425-0",
  issn="1884-4049",
  url="https://www.nature.com/articles/s41427-022-00425-0"
}