Publication result detail

Swarming Magnetic Photoactive Microrobots for Dental Implant Biofilm Eradication

MAYORGA-MARTINEZ, C.; ZELENKA, J.; KLÍMA, K.; MAYORGA BURREZO, P.; HOANG, L.; RUML, T.; PUMERA, M.

Original Title

Swarming Magnetic Photoactive Microrobots for Dental Implant Biofilm Eradication

English Title

Swarming Magnetic Photoactive Microrobots for Dental Implant Biofilm Eradication

Type

WoS Article

Original Abstract

Titanium dental implants are a multibillion dollar market in the United States alone. The growth of a bacterial biofilm on a dental implant can cause gingivitis, implant loss, and expensive subsequent care. Herein, we demonstrate the efficient eradication of dental biofilm on titanium dental implants via swarming magnetic microrobots based on ferromagnetic (Fe3O4) and photoactive (BiVO4) materials through polyethylenimine micelles. The ferromagnetic component serves as a propulsion force using a transversal rotating magnetic field while BiVO4 is the photoactive generator of reactive oxygen species to eradicate the biofilm colonies. Such photoactive magnetically powered, precisely navigated microrobots are able to destroy biofilm colonies on titanium implants, demonstrating their use in precision medicine.

English abstract

Titanium dental implants are a multibillion dollar market in the United States alone. The growth of a bacterial biofilm on a dental implant can cause gingivitis, implant loss, and expensive subsequent care. Herein, we demonstrate the efficient eradication of dental biofilm on titanium dental implants via swarming magnetic microrobots based on ferromagnetic (Fe3O4) and photoactive (BiVO4) materials through polyethylenimine micelles. The ferromagnetic component serves as a propulsion force using a transversal rotating magnetic field while BiVO4 is the photoactive generator of reactive oxygen species to eradicate the biofilm colonies. Such photoactive magnetically powered, precisely navigated microrobots are able to destroy biofilm colonies on titanium implants, demonstrating their use in precision medicine.

Keywords

bacterial biofilm; photoactive material; ferromagnetic material; polymer micelles; micromotors

Key words in English

bacterial biofilm; photoactive material; ferromagnetic material; polymer micelles; micromotors

Authors

MAYORGA-MARTINEZ, C.; ZELENKA, J.; KLÍMA, K.; MAYORGA BURREZO, P.; HOANG, L.; RUML, T.; PUMERA, M.

RIV year

2023

Released

28.06.2022

Publisher

AMER CHEMICAL SOC

Location

WASHINGTON

ISBN

1936-086X

Periodical

ACS Nano

Volume

16

Number

6

State

United States of America

Pages from

8694

Pages to

8703

Pages count

10

URL

https://pubs.acs.org/doi/10.1021/acsnano.2c02516

BibTex

@article{BUT178683,
  author="Carmen C. {Mayorga-Martinez} and Jaroslav {Zelenka} and Karel {Klíma} and Paula {Mayorga Burrezo} and Lan {Hoang} and Tomáš {Ruml} and Martin {Pumera}",
  title="Swarming Magnetic Photoactive Microrobots for Dental Implant Biofilm Eradication",
  journal="ACS Nano",
  year="2022",
  volume="16",
  number="6",
  pages="8694--8703",
  doi="10.1021/acsnano.2c02516",
  issn="1936-0851",
  url="https://pubs.acs.org/doi/10.1021/acsnano.2c02516"
}