Publication result detail

Characterization of the Morphological Nature of Hollow Spray Dried Dispersion Particles Using X-ray Submicron-Computed Tomography

GAMBLE, J.; TOBYN, M.; ZHANG, S.; ZHU, A.; ŠALPLACHTA, J.; MATULA, J.; ZIKMUND, T.; KAISER, J.; OBERTA, P.

Original Title

Characterization of the Morphological Nature of Hollow Spray Dried Dispersion Particles Using X-ray Submicron-Computed Tomography

English Title

Characterization of the Morphological Nature of Hollow Spray Dried Dispersion Particles Using X-ray Submicron-Computed Tomography

Type

WoS Article

Original Abstract

The aim of this work was to investigate the feasibility of submicronCT to enable improved characterization of the morphological nature of SDD materials. The manuscript also suggests possible approaches to utilize the measured data in order to better understand the range of particle properties present within a sample. It is hoped that an improved handle on the SDD particle properties will enable improved linking of particle properties with processing conditions and downstream behaviour, and consequently, enable improved modelling of spray drying processes.

English abstract

The aim of this work was to investigate the feasibility of submicronCT to enable improved characterization of the morphological nature of SDD materials. The manuscript also suggests possible approaches to utilize the measured data in order to better understand the range of particle properties present within a sample. It is hoped that an improved handle on the SDD particle properties will enable improved linking of particle properties with processing conditions and downstream behaviour, and consequently, enable improved modelling of spray drying processes.

Keywords

spray drying; materials science; morphology; physical characterization; solid dispersion

Key words in English

spray drying; materials science; morphology; physical characterization; solid dispersion

Authors

GAMBLE, J.; TOBYN, M.; ZHANG, S.; ZHU, A.; ŠALPLACHTA, J.; MATULA, J.; ZIKMUND, T.; KAISER, J.; OBERTA, P.

RIV year

2022

Released

18.11.2021

Publisher

SPRINGER

Location

NEW YORK

ISBN

1530-9932

Periodical

AAPS PHARMSCITECH

Volume

23

Number

1

State

United States of America

Pages from

1

Pages to

7

Pages count

7

URL

https://link.springer.com/article/10.1208%2Fs12249-021-02184-7

BibTex

@article{BUT173274,
  author="GAMBLE, J. and TOBYN, M. and ZHANG, S. and ZHU, A. and ŠALPLACHTA, J. and MATULA, J. and ZIKMUND, T. and KAISER, J. and OBERTA, P.",
  title="Characterization of the Morphological Nature of Hollow Spray Dried Dispersion Particles Using X-ray Submicron-Computed Tomography",
  journal="AAPS PHARMSCITECH",
  year="2021",
  volume="23",
  number="1",
  pages="1--7",
  doi="10.1208/s12249-021-02184-7",
  issn="1530-9932",
  url="https://link.springer.com/article/10.1208%2Fs12249-021-02184-7"
}