Publication result detail

Rhodotorula kratochvilovae CCY 20-2-26-The Source of Multifunctional Metabolites

BYRTUSOVÁ, D.; SZOTKOWSKI, M.; KUROWSKA, K.; SHAPAVAL, V.; MÁROVÁ, I.

Original Title

Rhodotorula kratochvilovae CCY 20-2-26-The Source of Multifunctional Metabolites

English Title

Rhodotorula kratochvilovae CCY 20-2-26-The Source of Multifunctional Metabolites

Type

WoS Article

Original Abstract

Multifunctional biomass is able to provide more than one valuable product, and thus, it is attractive in the field of microbial biotechnology due to its economic feasibility. Carotenogenic yeasts are effective microbial factories for the biosynthesis of a broad spectrum of biomolecules that can be used in the food and feed industry and the pharmaceutical industry, as well as a source of biofuels. In the study, we examined the effect of different nitrogen sources, carbon sources and CN ratios on the co-production of intracellular lipids, carotenoids, beta-glucans and extracellular glycolipids. Yeast strain R. kratochvilovae CCY 20-2-26 was identified as the best co-producer of lipids (66.7 +/- 1.5% of DCW), exoglycolipids (2.42 +/- 0.08 g/L), beta-glucan (11.33 +/- 1.34% of DCW) and carotenoids (1.35 +/- 0.11 mg/g), with a biomass content of 15.2 +/- 0.8 g/L, by using the synthetic medium with potassium nitrate and mannose as a carbon source. It was shown that an increased C/N ratio positively affected the biomass yield and production of lipids and beta-glucans.

English abstract

Multifunctional biomass is able to provide more than one valuable product, and thus, it is attractive in the field of microbial biotechnology due to its economic feasibility. Carotenogenic yeasts are effective microbial factories for the biosynthesis of a broad spectrum of biomolecules that can be used in the food and feed industry and the pharmaceutical industry, as well as a source of biofuels. In the study, we examined the effect of different nitrogen sources, carbon sources and CN ratios on the co-production of intracellular lipids, carotenoids, beta-glucans and extracellular glycolipids. Yeast strain R. kratochvilovae CCY 20-2-26 was identified as the best co-producer of lipids (66.7 +/- 1.5% of DCW), exoglycolipids (2.42 +/- 0.08 g/L), beta-glucan (11.33 +/- 1.34% of DCW) and carotenoids (1.35 +/- 0.11 mg/g), with a biomass content of 15.2 +/- 0.8 g/L, by using the synthetic medium with potassium nitrate and mannose as a carbon source. It was shown that an increased C/N ratio positively affected the biomass yield and production of lipids and beta-glucans.

Keywords

Rhodotorula kratochvilovae; lipids; extracellular glycolipids; carotenoids; beta-glucan

Key words in English

Rhodotorula kratochvilovae; lipids; extracellular glycolipids; carotenoids; beta-glucan

Authors

BYRTUSOVÁ, D.; SZOTKOWSKI, M.; KUROWSKA, K.; SHAPAVAL, V.; MÁROVÁ, I.

RIV year

2022

Released

11.07.2021

Publisher

MDPI

Location

BASEL

ISBN

2076-2607

Periodical

Microorganisms

Volume

9

Number

6

State

Swiss Confederation

Pages from

1

Pages to

18

Pages count

18

URL

https://www.mdpi.com/2076-2607/9/6/1280

Full text in the Digital Library

http://hdl.handle.net/11012/202241

BibTex

@article{BUT172746,
  author="Dana {Byrtusová} and Martin {Szotkowski} and Klára {Kurowska} and Volha {Shapaval} and Ivana {Márová}",
  title="Rhodotorula kratochvilovae CCY 20-2-26-The Source of Multifunctional Metabolites",
  journal="Microorganisms",
  year="2021",
  volume="9",
  number="6",
  pages="1--18",
  doi="10.3390/microorganisms9061280",
  url="https://www.mdpi.com/2076-2607/9/6/1280"
}

Documents

microorganisms-09-01280-v2