Publication detail

Microbubbles as safety issue of novel cathetrization ablation methods

PEŠL, M. VÍTEČEK, J. ČERNÍK, M. NOVOTNÁ, V. ČERVINKA, D. CALUORI, G. KULÍK, T. KUBALA, L. STÁREK, Z.

Original Title

Microbubbles as safety issue of novel cathetrization ablation methods

Type

abstract

Language

English

Original Abstract

The gaseous micro bubbles release is the main complication of left sided cardiac catheter ablation. Cerebral vessel occlusion results in subclinical "silent" ischemia or manifests as stroke, however other organs may also be affected. Active search for microbubble formation – caused by either manipulation or nature of utilized energy – is essential in all developing and established catheterization methods. Radiofrequency ablation (RF) cause gaseous bubble formation during excessive heating, while, pulsed electric field (PEF electroporation) were reported to elicit bubbles during milliseconds of application. We proposed microbubble formation description during catheter RF and PEF energy application using were quadrupolar ablation catheters with/without active flushing and high-speed microscope mounted camera (ORCA- Flash4.0 LT, Hamamatsu). Size, volume and number of microbubbles were quantified using image processing. Dynamics of gas formation in the bubbles was followed up to 20 seconds after the ablation energy application.

Keywords

arrhythmia, catheterization ablation, complication, air embolism, microbubbles

Authors

PEŠL, M.; VÍTEČEK, J.; ČERNÍK, M.; NOVOTNÁ, V.; ČERVINKA, D.; CALUORI, G.; KULÍK, T.; KUBALA, L.; STÁREK, Z.

Released

29. 11. 2020

Pages from

245

Pages to

245

Pages count

1

URL

https://www.embec2020.org/wp-content/uploads/2020/11/EMBEC2020_Book_of_Abstracts.pdf

BibTex

@misc{BUT165915,
  author="PEŠL, M. and VÍTEČEK, J. and ČERNÍK, M. and NOVOTNÁ, V. and ČERVINKA, D. and CALUORI, G. and KULÍK, T. and KUBALA, L. and STÁREK, Z.",
  title="Microbubbles as safety issue of novel cathetrization ablation methods",
  booktitle="The Abstract Book of EMBEC 2020",
  year="2020",
  pages="245--245",
  url="https://www.embec2020.org/wp-content/uploads/2020/11/EMBEC2020_Book_of_Abstracts.pdf",
  note="abstract"
}