Publication result detail

Fludeoxyglucose Metabolism Modeling: An Overview

CHALUPA, D.; MIKULKA, J.

Original Title

Fludeoxyglucose Metabolism Modeling: An Overview

English Title

Fludeoxyglucose Metabolism Modeling: An Overview

Type

Paper in proceedings (conference paper)

Original Abstract

Pharmacokinetic modeling of glucose provides the means to quantify local metabolic rate in various tissues. The 2-deoxy-2-(18F)fluoro-D-glucose (FDG) radiopharmaceutical allows researchers to use and optimize numerical models for this purpose in Positron Emission Tomography (PET) clinical studies. This work provides an insight into how the models were created and historically updated. It describes some of the models in detail and mentions their drawbacks and subsequent solutions. The invasivity of the early metabolic rate estimation methods is mentioned and numerical and graphical solutions are presented.

English abstract

Pharmacokinetic modeling of glucose provides the means to quantify local metabolic rate in various tissues. The 2-deoxy-2-(18F)fluoro-D-glucose (FDG) radiopharmaceutical allows researchers to use and optimize numerical models for this purpose in Positron Emission Tomography (PET) clinical studies. This work provides an insight into how the models were created and historically updated. It describes some of the models in detail and mentions their drawbacks and subsequent solutions. The invasivity of the early metabolic rate estimation methods is mentioned and numerical and graphical solutions are presented.

Keywords

Fludeoxyglucose; Metabolism; Modeling; PET; Pharmacokinetics; Signal Processing; Simultaneous Estimation

Key words in English

Fludeoxyglucose; Metabolism; Modeling; PET; Pharmacokinetics; Signal Processing; Simultaneous Estimation

Authors

CHALUPA, D.; MIKULKA, J.

RIV year

2019

Released

12.05.2018

ISBN

978-83-7663-250-6

Book

Proceedings of the IIPhDW 2018

Pages from

1

Pages to

3

Pages count

3

BibTex

@inproceedings{BUT147551,
  author="Daniel {Chalupa} and Jan {Mikulka}",
  title="Fludeoxyglucose Metabolism Modeling: An Overview",
  booktitle="Proceedings of the IIPhDW 2018",
  year="2018",
  pages="1--3",
  doi="10.1109/IIPHDW.2018.8388232",
  isbn="978-83-7663-250-6"
}