Publication result detail

Interaction of Graphene Oxide with Proteins and Applications of their Conjugates

ŠIMŠÍKOVÁ, M.; ŠIKOLA, T.

Original Title

Interaction of Graphene Oxide with Proteins and Applications of their Conjugates

English Title

Interaction of Graphene Oxide with Proteins and Applications of their Conjugates

Type

Peer-reviewed article not indexed in WoS or Scopus

Original Abstract

Graphene oxide (GO) has abundant surface oxygen-containing groups such as epoxide, hydroxyl, and carboxylic groups; it can be prepared through the oxidative intercalation and exfoliation of graphite on a mass scale. Owing to the enriched surface functionalities, the GO is water-soluble and chemically versatile. The surface functional groups can also provide plenty of reaction sites for linking nanoparticles, proteins, enzymes, peptides, bacteria, cells, and nucleic acids through covalent and non-covalent binding. GO has been used as a matrix for protein immobilization in different biotechnological applications such as fluorescence- or electrochemical-based sensors, labeling and imaging, therapy, and targeted delivery. This paper reviews the main strategies for the assembly of proteins onto graphene oxide surface and their applications, especially in the biomedical area.

English abstract

Graphene oxide (GO) has abundant surface oxygen-containing groups such as epoxide, hydroxyl, and carboxylic groups; it can be prepared through the oxidative intercalation and exfoliation of graphite on a mass scale. Owing to the enriched surface functionalities, the GO is water-soluble and chemically versatile. The surface functional groups can also provide plenty of reaction sites for linking nanoparticles, proteins, enzymes, peptides, bacteria, cells, and nucleic acids through covalent and non-covalent binding. GO has been used as a matrix for protein immobilization in different biotechnological applications such as fluorescence- or electrochemical-based sensors, labeling and imaging, therapy, and targeted delivery. This paper reviews the main strategies for the assembly of proteins onto graphene oxide surface and their applications, especially in the biomedical area.

Keywords

Graphene Oxide; Protein; Interaction; Conjugate

Key words in English

Graphene Oxide; Protein; Interaction; Conjugate

Authors

ŠIMŠÍKOVÁ, M.; ŠIKOLA, T.

RIV year

2018

Released

08.03.2017

ISBN

2377-4282

Periodical

Journal of Nanomedicine Research

Volume

5

Number

2

State

United States of America

Pages from

1

Pages to

4

Pages count

4

BibTex

@article{BUT139931,
  author="Michaela {Šimšíková} and Tomáš {Šikola}",
  title="Interaction of Graphene Oxide with Proteins and Applications of their Conjugates",
  journal="Journal of Nanomedicine Research",
  year="2017",
  volume="5",
  number="2",
  pages="1--4",
  doi="10.15406/jnmr.2017.05.00109",
  issn="2377-4282"
}