Publication detail

EXPERIMENTAL USE OF NOVEL PULSE GENERATOR FOR IRREVERSIBLE ELECTROPORATION

Veronika Novotná

Original Title

EXPERIMENTAL USE OF NOVEL PULSE GENERATOR FOR IRREVERSIBLE ELECTROPORATION

Type

conference paper

Language

English

Original Abstract

Irreversible electroporation (IRE) is a relatively new technique for minimal invasive nonthermal ablation treatment of solid tumors. This article describes basics of IRE and available devices for this technique. The parameters of commercial NanoKnife IRE generator are verified and the unique experimental IRE generator developed at the Brno University of Technology is presented in this paper. Further, there is a comparison of thermal effects on a target tissue of commonly used radiofrequency ablation (RFA) and the novel IRE generator using an infrared camera. All experiments were performed ex vivo on a porcine liver. The difference in maximum temperature between the output powers used was 17.8 °C with RFA and 3 °C with IRE. This is a significant difference and shows the IRE’s capability of liver tissue ablation without thermal damage. The new IRE generator is also capable of replacing NanoKnife because of its features and versatility.

Keywords

Development, Irreversible Electroporation, Radiofrequency ablation, Infrared camera

Authors

Veronika Novotná

Released

27. 4. 2017

Publisher

Vysoké učení technické v Brně, Fakulta elektrotechniky a komunikačních

Location

první

ISBN

978-80-214-5496-5

Book

Proceedings of the 23nd Conference STUDENT EEICT 2017

Edition number

1

Pages from

568

Pages to

572

Pages count

5

BibTex

@inproceedings{BUT135360,
  author="Veronika {Novotná}",
  title="EXPERIMENTAL USE OF NOVEL PULSE GENERATOR FOR IRREVERSIBLE ELECTROPORATION",
  booktitle="Proceedings of the 23nd Conference STUDENT EEICT 2017",
  year="2017",
  number="1",
  pages="568--572",
  publisher="Vysoké učení technické v Brně, Fakulta elektrotechniky a komunikačních",
  address="první",
  isbn="978-80-214-5496-5"
}