Publication result detail

Prediction of localized aerosol deposition in a realistic replica of human airways using experimental data and numerical simulation

LÍZAL, F.; ELCNER, J.; BĚLKA, M.; JEDELSKÝ, J.; JÍCHA, M.

Original Title

Prediction of localized aerosol deposition in a realistic replica of human airways using experimental data and numerical simulation

English Title

Prediction of localized aerosol deposition in a realistic replica of human airways using experimental data and numerical simulation

Type

Paper in proceedings (conference paper)

Original Abstract

The presence of aerosol deposition hot-spots in human airways presumably contributes to development of various diseases. The overall aerosol deposition in human lungs can be predicted with sufficient accuracy nowadays. However, the prediction of localized aerosol deposition poses arduous challenge, namely in diseased lungs. Numerical simulation is considered to be a promising tool for the successful prediction. Yet, the validation of such simulations is difficult to perform, as not enough experimental data acquired using realistic airway replicas is available. This paper presents a first comparison of localized deposition measurement and simulation performed on the identical realistic geometry. The analysis indicates that both approaches yield similar results for low Reynolds number flows.

English abstract

The presence of aerosol deposition hot-spots in human airways presumably contributes to development of various diseases. The overall aerosol deposition in human lungs can be predicted with sufficient accuracy nowadays. However, the prediction of localized aerosol deposition poses arduous challenge, namely in diseased lungs. Numerical simulation is considered to be a promising tool for the successful prediction. Yet, the validation of such simulations is difficult to perform, as not enough experimental data acquired using realistic airway replicas is available. This paper presents a first comparison of localized deposition measurement and simulation performed on the identical realistic geometry. The analysis indicates that both approaches yield similar results for low Reynolds number flows.

Keywords

aerosol deposition, human lungs, human airways, computational fluid mechanics, experiment

Key words in English

aerosol deposition, human lungs, human airways, computational fluid mechanics, experiment

Authors

LÍZAL, F.; ELCNER, J.; BĚLKA, M.; JEDELSKÝ, J.; JÍCHA, M.

RIV year

2018

Released

15.11.2016

Publisher

EDP Sciences

Book

EPJ Web of Conferences

ISBN

2100-014X

Periodical

EPJ Web of Conferences

Volume

143

State

French Republic

Pages from

1

Pages to

4

Pages count

4

URL

https://www.epj-conferences.org/articles/epjconf/abs/2017/12/epjconf_efm2017_02067/epjconf_efm2017_02067.html

Full text in the Digital Library

http://hdl.handle.net/11012/70127

BibTex

@inproceedings{BUT131497,
  author="František {Lízal} and Jakub {Elcner} and Miloslav {Bělka} and Jan {Jedelský} and Miroslav {Jícha}",
  title="Prediction of localized aerosol deposition in a realistic replica of human airways using experimental data and numerical simulation",
  booktitle="EPJ Web of Conferences",
  year="2016",
  journal="EPJ Web of Conferences",
  volume="143",
  pages="1--4",
  publisher="EDP Sciences",
  doi="10.1051/epjconf/201714302067",
  issn="2100-014X",
  url="https://www.epj-conferences.org/articles/epjconf/abs/2017/12/epjconf_efm2017_02067/epjconf_efm2017_02067.html"
}

Documents

epjconf_efm2017_02067