Publication result detail

Using UV-VIS spectrophotometry for determining ecotoxicity of selected non-steroidal anti-inflammatory drugs

ČAPKA, L.; ZLÁMALOVÁ GARGOŠOVÁ, H.; VÁVROVÁ, M.

Original Title

Using UV-VIS spectrophotometry for determining ecotoxicity of selected non-steroidal anti-inflammatory drugs

English Title

Using UV-VIS spectrophotometry for determining ecotoxicity of selected non-steroidal anti-inflammatory drugs

Type

WoS Article

Original Abstract

This paper presents the use of UV-VIS spectrophotometry as a means of determining ecotoxicity. The method is based on spectrophotometric measuring of micro-algae Pseudokirchneriella subcapitata in water suspension. Six non-steroidal anti-inflammatory drugs (paracetamol, diclofenac, salicylic acid, ibuprofen, naproxen and ketoprofen) were selected as target compounds because they are the most commonly used human pharmaceuticals, which also means they are significant environmental pollutants. The 72hEC50 method was chosen for determination of ecotoxicity. The results reveal paracetamol (104 mg/L) and particularly ketoprofen (9 mg/L) as potentially ecotoxic compounds for aquatic organisms.

English abstract

This paper presents the use of UV-VIS spectrophotometry as a means of determining ecotoxicity. The method is based on spectrophotometric measuring of micro-algae Pseudokirchneriella subcapitata in water suspension. Six non-steroidal anti-inflammatory drugs (paracetamol, diclofenac, salicylic acid, ibuprofen, naproxen and ketoprofen) were selected as target compounds because they are the most commonly used human pharmaceuticals, which also means they are significant environmental pollutants. The 72hEC50 method was chosen for determination of ecotoxicity. The results reveal paracetamol (104 mg/L) and particularly ketoprofen (9 mg/L) as potentially ecotoxic compounds for aquatic organisms.

Keywords

Ecotoxicity, non-steroidal anti-inflammatory drugs, UV-VIS spectrophotometry

Key words in English

Ecotoxicity, non-steroidal anti-inflammatory drugs, UV-VIS spectrophotometry

Authors

ČAPKA, L.; ZLÁMALOVÁ GARGOŠOVÁ, H.; VÁVROVÁ, M.

RIV year

2016

Released

01.12.2015

ISBN

1018-4619

Periodical

Fresenius Environmental Bulletin

Volume

24

Number

12

State

Federal Republic of Germany

Pages from

4758

Pages to

4762

Pages count

5

BibTex

@article{BUT119157,
  author="Lukáš {Alexa} and Helena {Zlámalová Gargošová} and Milada {Vávrová}",
  title="Using UV-VIS spectrophotometry for determining ecotoxicity of selected non-steroidal anti-inflammatory drugs",
  journal="Fresenius Environmental Bulletin",
  year="2015",
  volume="24",
  number="12",
  pages="4758--4762",
  issn="1018-4619"
}