Detail publikačního výsledku

Study of Protein Conjugation with Different Types of CdTe Quantum Dots

CHOMOUCKÁ, J.; DRBOHLAVOVÁ, J.; VACULOVIČOVÁ, M.; MAJZLÍKOVÁ, P.; PRÁŠEK, J.; PEKÁREK, J.; HUBÁLEK, J.

Original Title

Study of Protein Conjugation with Different Types of CdTe Quantum Dots

English Title

Study of Protein Conjugation with Different Types of CdTe Quantum Dots

Type

Conference proceedings

Original Abstract

In this paper, the interaction between bovine serum albumin (BSA) and water soluble CdTe quantum dots (QDs) modified with different ligands (3-mercaptoacetic acid, thioglycolic acid and glutathione) was studied using the fluorescence spectroscopy. It was found that the presence of QDs led to a strong quenching effect of BSA, which could be explained by a covalent interaction between the protein and the quencher, demonstrating the formation of QDs-BSA bioconjugates.

English abstract

In this paper, the interaction between bovine serum albumin (BSA) and water soluble CdTe quantum dots (QDs) modified with different ligands (3-mercaptoacetic acid, thioglycolic acid and glutathione) was studied using the fluorescence spectroscopy. It was found that the presence of QDs led to a strong quenching effect of BSA, which could be explained by a covalent interaction between the protein and the quencher, demonstrating the formation of QDs-BSA bioconjugates.

Keywords

quantum dots; conjugation; protein; bovine serum albumin; glutathione; 3-mercaptoacetic acid; thioglycolic acid

Key words in English

quantum dots; conjugation; protein; bovine serum albumin; glutathione; 3-mercaptoacetic acid; thioglycolic acid

Authors

CHOMOUCKÁ, J.; DRBOHLAVOVÁ, J.; VACULOVIČOVÁ, M.; MAJZLÍKOVÁ, P.; PRÁŠEK, J.; PEKÁREK, J.; HUBÁLEK, J.

RIV year

2014

Released

25.08.2013

Publisher

IARIA

Location

Barcelona

ISBN

978-1-61208-303-2

Book

Conference Proceedings - ICQNM 2013

Edition

1

Pages from

18

Pages to

22

Pages count

5

Full text in the Digital Library

http://hdl.handle.net/

BibTex

@proceedings{BUT103693,
  editor="Jana {Pekárková} and Jana {Drbohlavová} and Markéta {Vaculovičová} and Petra {Majzlíková} and Jan {Prášek} and Jan {Pekárek} and Jaromír {Hubálek}",
  title="Study of Protein Conjugation with Different Types of CdTe Quantum Dots",
  year="2013",
  series="1",
  pages="18--22",
  publisher="IARIA",
  address="Barcelona",
  isbn="978-1-61208-303-2"
}