Applied result detail

R/Bioconductor package for identification of triplex-forming sequences

HON, J.; LEXA, M.; MARTÍNEK, T.; RAJDL, K.

Original Title

R/Bioconductor package for identification of triplex-forming sequences

English Title

R/Bioconductor package for identification of triplex-forming sequences

Type

Software

Abstract

This package provides functions for identification and visualization of potential intramolecular triplex patterns in DNA sequence. The main functionality is to detect the positions of subsequences capable of folding into an intramolecular triplex (H-DNA) in a much larger sequence. The potential H-DNA (triplexes) should be made of as many cannonical nucleotide triplets as possible. The package includes visualization showing the exact base-pairing in 1D, 2D or 3D.

Abstract in English

This package provides functions for identification and visualization of potential intramolecular triplex patterns in DNA sequence. The main functionality is to detect the positions of subsequences capable of folding into an intramolecular triplex (H-DNA) in a much larger sequence. The potential H-DNA (triplexes) should be made of as many cannonical nucleotide triplets as possible. The package includes visualization showing the exact base-pairing in 1D, 2D or 3D.

Keywords

H-DNA; R/Bioconductor; pattern matching; dynamic programming; triplex; searching; annotation

Key words in English

H-DNA; R/Bioconductor; pattern matching; dynamic programming; triplex; searching; annotation

Location

http://www.bioconductor.org/packages/release/bioc/html/triplex.html

Licence fee

Use of the result by another entity is possible without acquiring a license in some cases

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