Glioblastoma is among the deadliest brain cancers, requiring new therapeutic strategies. This project develops a bioelectronic platform that continuously generates pharmacological doses of hydrogen peroxide (H2O2) using PEDOT electrodes, exploiting cancer-specific redox imbalance. By studying cell death mechanisms in 2D and 3D glioblastoma models, we aim to establish selective, controllable ROS therapy with strong potential for clinical translation.

CEITEC VUT-J-26-9096

Czech

Nečasová Markéta, Ing. - principal person responsible
Glowacki Eric Daniel, prof., Ph.D. - fellow researcher

Central European Institute of Technology BUT
- responsible department (30.1.2026 - not assigned)
Central European Institute of Technology BUT
- beneficiary (1.1.2026 - 31.12.2026)

Responsibility: Nečasová Markéta, Ing.