Project detail

Advancing Skin Regeneration: Development of 3D Collagen-Based Scaffolds Loaded with HIF Inhibitor for Improved Vascularization and Wound Healing

Duration: 1.3.2025 — 28.2.2026

Funding resources

Vysoké učení technické v Brně - Vnitřní projekty VUT

On the project

This study explores collagen-based porous foams for regenerative medicine. A porous foam scaffold, composed of collagen and carboxymethyl cellulose (CMC), was designed to mimic the epidermis and enhance vascularization. The scaffold will be loaded with dimethyloxalylglycine (DMOG) to investigate its effects on hypoxia response and angiogenesis. Additionally, DMOG’s influence on spheroids will be assessed for hypoxia and gene expression in cooperation with the University of Sheffield.

Mark

CEITEC VUT-J-25-8891

Default language

Czech

People responsible

Izsák Dávid, Ing. - principal person responsible
Pavliňáková Veronika, Mgr., Ph.D. - fellow researcher

Units

Advanced Biomaterials
- responsible department (3.3.2025 - not assigned)
Central European Institute of Technology BUT
- responsible department (31.1.2025 - 3.3.2025)
Advanced Biomaterials
- beneficiary (1.1.2025 - 31.12.2025)

Responsibility: Izsák Dávid, Ing.