Project detail
Advancing Skin Regeneration: Development of 3D Collagen-Based Scaffolds Loaded with HIF Inhibitor for Improved Vascularization and Wound Healing
Duration: 1.3.2025 — 28.2.2026
Funding resources
Vysoké učení technické v Brně - Vnitřní projekty VUT
On the project
This study explores collagen-based porous foams for regenerative medicine. A porous foam scaffold, composed of collagen and carboxymethyl cellulose (CMC), was designed to mimic the epidermis and enhance vascularization. The scaffold will be loaded with dimethyloxalylglycine (DMOG) to investigate its effects on hypoxia response and angiogenesis. Additionally, DMOG’s influence on spheroids will be assessed for hypoxia and gene expression in cooperation with the University of Sheffield.
Mark
CEITEC VUT-J-25-8891
Default language
Czech
People responsible
Izsák Dávid, Ing. - principal person responsible
Pavliňáková Veronika, Mgr., Ph.D. - fellow researcher
Units
Advanced Biomaterials
- responsible department (3.3.2025 - not assigned)
Central European Institute of Technology BUT
- responsible department (31.1.2025 - 3.3.2025)
Advanced Biomaterials
- beneficiary (1.1.2025 - 31.12.2025)
Responsibility: Izsák Dávid, Ing.