Project detail

Methylation detection in Aneurinibacillus bacteria genome using nanopore sequencing

Duration: 01.03.2024 — 28.02.2025

Funding resources

Brno University of Technology - Vnitřní projekty VUT

- whole funder (2024-01-01 - 2025-12-31)

On the project

The submitted project aims to develop a robust methylation detection pipeline utilizing ONT sequencing for in-depth analysis of Aneurinibacillus sp. methylomes. It is centered on a comparative analysis of two sequencing techniques (ONT and PacBio) for methylation detection. This serves as foundational knowledge to create a new neural network aimed at enhancing the accuracy of ONT. This endeavor will provide us with novel insights into the role of methylomes in bacteria cultivated under stress conditions.

Mark

FCH/FEKT-J-24-8516

Default language

Czech

People responsible

Obruča Stanislav, prof. Ing., Ph.D. - fellow researcher
Řeháková Veronika, Ing. - fellow researcher
Sedlář Karel, doc. Mgr. Ing., Ph.D. - fellow researcher
Umair Mohammad - principal person responsible

Units

Faculty of Electrical Engineering and Communication
- beneficiary (2024-01-01 - 2024-12-31)
Department of Biomedical Engineering
- internal (2024-01-01 - 2024-12-31)
Faculty of Chemistry
- internal (2024-01-01 - 2024-12-31)
Institute of Food Science and Biotechnology
- internal (2024-01-01 - 2024-12-31)

Results

UMAIR, M.; ŘEHÁKOVÁ, V.; BUCHTÍKOVÁ, I.; BEZDÍČEK, M.; OBRUČA, S.; SEDLÁŘ, K. Bioinformatics study of the third generation sequencing platforms applied on a thermophile. Proceedings I of the 30 th Conference STUDENT EEICT 2024. 1. 2024. ISBN: 978-80-214-6231-1.
Detail