Course detail
Introduction to Magnetic Resonance, with focus on EPR: Experiments, Applications and Supervision of
CEITEC VUT-DS124AAcad. year: 2020/2021
Not applicable.
Language of instruction
English
Mode of study
Not applicable.
Guarantor
Learning outcomes of the course unit
Not applicable.
Prerequisites
Not applicable.
Co-requisites
Not applicable.
Planned learning activities and teaching methods
block of lectures in one week
Assesment methods and criteria linked to learning outcomes
Not applicable.
Course curriculum
History – Key persons/Experiments
- Zeeman effect
- Stern-Gerlach experiment
- First EPR experiment – Zavoisky
Motivation – impact of the method on society and overview of applications
Basic principles of Magnetic resonance (Intro to Andriy Marko course)
- Nuclear and Electronic Spin
- Magnetization and its manipulation
- Bloch equations
- Spin Hamiltonian – size of probed interactions
Difference between Nuclear Magnetic Resonance (NMR) and Electron Paramagnetic Resonance (EPR or ESR)
Experimental arrangement
- Continuous wave experiments
- Pulsed experiments – T1 and T2 measurements, ES-EPR
- Field domain vs. Frequency domain
- High magnetic fields experiments
Basic examples
- EPR on radicals – hyperfine interaction
- NMR of coupled hydrogens – J-couplings
- 2D experiments
Principles of Magnetic Resonance Imaging (MRI)
- Gradient fields
- T1 and T2 weighted pictures
Detailed description of experimental technique
- RF and MW technology, active and passive components
- Generation of high power MW sources and MW cavities
- Generation of Magnetic Fields (resistive, superconducting, hybrids, pulsed field techniques)
Detailed description of individual experiments
- REFINE experiment
- HFEPR on Single Molecular Magnets – Fe4 example
- PELDOR experiments – deformation of DNA
Current trends in Magnetic Resonance
- Dynamic Nuclear Polarization (DNP) – enhancement of NMR signal
- More advance pulsed excitations in EPR – distance measurements
- Rapid scan ESR
- Zeeman effect
- Stern-Gerlach experiment
- First EPR experiment – Zavoisky
Motivation – impact of the method on society and overview of applications
Basic principles of Magnetic resonance (Intro to Andriy Marko course)
- Nuclear and Electronic Spin
- Magnetization and its manipulation
- Bloch equations
- Spin Hamiltonian – size of probed interactions
Difference between Nuclear Magnetic Resonance (NMR) and Electron Paramagnetic Resonance (EPR or ESR)
Experimental arrangement
- Continuous wave experiments
- Pulsed experiments – T1 and T2 measurements, ES-EPR
- Field domain vs. Frequency domain
- High magnetic fields experiments
Basic examples
- EPR on radicals – hyperfine interaction
- NMR of coupled hydrogens – J-couplings
- 2D experiments
Principles of Magnetic Resonance Imaging (MRI)
- Gradient fields
- T1 and T2 weighted pictures
Detailed description of experimental technique
- RF and MW technology, active and passive components
- Generation of high power MW sources and MW cavities
- Generation of Magnetic Fields (resistive, superconducting, hybrids, pulsed field techniques)
Detailed description of individual experiments
- REFINE experiment
- HFEPR on Single Molecular Magnets – Fe4 example
- PELDOR experiments – deformation of DNA
Current trends in Magnetic Resonance
- Dynamic Nuclear Polarization (DNP) – enhancement of NMR signal
- More advance pulsed excitations in EPR – distance measurements
- Rapid scan ESR
Work placements
Not applicable.
Aims
To give overall introduction to magnetic resonance techniques: NMR and EPR, its applications, experimental setups and currents trends in the field. The focus is more towards EPR/ESR. The lecture can be supported by practical courses on X-band spectrometer at CEITEC BUT (building C).
Specification of controlled education, way of implementation and compensation for absences
Not applicable.
Recommended optional programme components
Not applicable.
Prerequisites and corequisites
Not applicable.
Basic literature
A. Abragam and B. Bleaney – Electron paramagnetic resonance of transition ions (Oxford Classic Text) (EN)
Arthur Schweiger and Gurnnar Jeschke – Principles of pulsed electron paramagnetic resonance (Oxford University Press) (EN)
James Keeler – Understanding NMR spectroscopy (Wiley, also free online)
John A. Weil and James R. Bolton – Electron Paramagnetic Resonance: Elementary Theory and Practical Applications (Wiley)
Peter Atkins – Physical Chemistry (11th edition, Oxford University Press)
Arthur Schweiger and Gurnnar Jeschke – Principles of pulsed electron paramagnetic resonance (Oxford University Press) (EN)
James Keeler – Understanding NMR spectroscopy (Wiley, also free online)
John A. Weil and James R. Bolton – Electron Paramagnetic Resonance: Elementary Theory and Practical Applications (Wiley)
Peter Atkins – Physical Chemistry (11th edition, Oxford University Press)
Recommended reading
Not applicable.