Course detail

Biophysical Chemistry

FCH-MCO_BFCHAcad. year: 2019/2020

The course focuses on the application of basic theoretical knowledge of physical chemistry to the biological systems. It represents a borderline course between physics, chemistry and biology, which allow obtaining molecular and structural perspective on biologically important and medically important pehnomena. Attention is drawn to an impact of the basic theoretical knowledge into analytical (advanced methods of study and interpretation of the structure and function of biopolymers) and application fields.

Learning outcomes of the course unit

Completing the course will result in knowledge on the essential principles of chemical thermodynamics and kinetics and their application to biological systems.


Not applicable.


Not applicable.

Recommended optional programme components

Not applicable.

Recommended or required reading

Kodíček M. Karpenko V.: Biofysikální chemie. Academia, 2000 (CS)
Kalous V. Pavlíček Z.:Biofyzikální chemie. SNTL, 1980 (CS)
Atkins, P.: Physical chemistry for the life sciences. Oxford University Press ;W. H. Freeman and Company, 2006 (EN)
Cooper A. Biophysical Chemistry. Royal Society of Chemistry, 2011. Online version available at: (EN)

Planned learning activities and teaching methods

The course uses teaching methods in form of Lecture - 2 teaching hours per week. The e-learning system (LMS Moodle) is available to teachers and students.

Assesment methods and criteria linked to learning outcomes

Exam: written and oral

Language of instruction


Work placements

Not applicable.

Course curriculum

Syllabus divided to weekly given lectures:

1. Introduction to biophysical chemistry
2., 3. Role of molecular interactions
4., 5. Biological thermodynamics
6. Bioenergetics
7., 8. Phase transitions in biological systems
9. Binding equilibria
10. Function and properties of biological membranes
11. Non-equilibrium thermodynamics
12., 13. Biological kinetics


The main aim of the course is to apply the basic knowledge and theories of physical chemistry (both from the thermodynamic and kinetic point of view) on the living systems and phenomena.

Specification of controlled education, way of implementation and compensation for absences

Attendance to lectures is not required but is recommended.

Classification of course in study plans

  • Programme NPCP_SCH Master's

    branch NPCO_SCH , 1. year of study, winter semester, 4 credits, compulsory-optional

  • Programme NKCP_SCH Master's

    branch NKCO_SCH , 1. year of study, winter semester, 4 credits, compulsory-optional

  • Programme NPCP_MA Master's

    branch NPCO_MA , 1. year of study, winter semester, 4 credits, compulsory-optional

  • Programme CKCP_CZV lifelong learning

    branch CKCO_CZV , 1. year of study, winter semester, 4 credits, compulsory-optional

Type of course unit



26 hours, optionally

Teacher / Lecturer


eLearning: opened course