Publication detail

Left Ventricular Myocardial Septal Pacing in Close Proximity to LBB Does Not Prolong the Duration of the Left Ventricular Lateral Wall Depolarization Compared to LBB Pacing

ČURILA, K. JURÁK, P. VERNOOY, K. JASTRZEBSKI, M. WALDAUF, P. PRINZEN, F. HALÁMEK, J. SUŠÁNKOVÁ, M. ZNOJILOVÁ, L. SMÍŠEK, R. KARCH, J. PLEŠINGER, F. MOSKAL, P. HECKMAN, L. MIZNER, J. VIŠČOR, I. VONDRA, V. LEINVEBER, P. OSMANČÍK, P.

Original Title

Left Ventricular Myocardial Septal Pacing in Close Proximity to LBB Does Not Prolong the Duration of the Left Ventricular Lateral Wall Depolarization Compared to LBB Pacing

Type

journal article in Web of Science

Language

English

Original Abstract

Background: Three different ventricular capture types are observed during left bundle branch pacing (LBBp). They are selective LBB pacing (sLBBp), non-selective LBB pacing (nsLBBp), and myocardial left septal pacing transiting from nsLBBp while decreasing the pacing output (LVSP). Study aimed to compare differences in ventricular depolarization between these captures using ultra-high-frequency electrocardiography (UHF-ECG). Methods: Using decremental pacing voltage output, we identified and studied nsLBBp, sLBBp, and LVSP in patients with bradycardia. Timing of ventricular activations in precordial leads was displayed using UHF-ECGs, and electrical dyssynchrony (e-DYS) was calculated as the difference between the first and last activation. The durations of local depolarizations (Vd) were determined as the width of the UHF-QRS complex at 50% of its amplitude. Results: In 57 consecutive patients, data were collected during nsLBBp (n = 57), LVSP (n = 34), and sLBBp (n = 23). Interventricular dyssynchrony (e-DYS) was significantly lower during LVSP −16 ms (−21; −11), than nsLBBp −24 ms (−28; −20) and sLBBp −31 ms (−36; −25). LVSP had the same V1d-V8d as nsLBBp and sLBBp except for V3d, which during LVSP was shorter than sLBBp; the mean difference −9 ms (−16; −1), p = 0.01. LVSP caused less interventricular dyssynchrony and the same or better local depolarization durations than nsLBBp and sLBBp irrespective of QRS morphology during spontaneous rhythm or paced QRS axis. Conclusions: In patients with bradycardia, LVSP in close proximity to LBB resulted in better interventricular synchrony than nsLBBp and sLBBp and did not significantly prolong depolarization of the left ventricular lateral wall.

Keywords

left bundle branch pacing, left septal myocardial pacing, UHF-ECG, dyssynchrony, depolarization duration

Authors

ČURILA, K.; JURÁK, P.; VERNOOY, K.; JASTRZEBSKI, M.; WALDAUF, P.; PRINZEN, F.; HALÁMEK, J.; SUŠÁNKOVÁ, M.; ZNOJILOVÁ, L.; SMÍŠEK, R.; KARCH, J.; PLEŠINGER, F.; MOSKAL, P.; HECKMAN, L.; MIZNER, J.; VIŠČOR, I.; VONDRA, V.; LEINVEBER, P.; OSMANČÍK, P.

Released

7. 12. 2021

Publisher

Frontiers

ISBN

2297-055X

Periodical

Frontiers in Cardiovascular Medicine

Year of study

8

Number

1

State

Swiss Confederation

Pages from

1

Pages to

10

Pages count

10

URL

https://www.frontiersin.org/article/10.3389/fcvm.2021.787414

Full text in the Digital Library

http://hdl.handle.net/11012/203233

BibTex

@article{BUT175204,
  author="Karol {Čurila} and Pavel {Jurák} and Kevin {Vernooy} and Marek {Jastrzebski} and Petr {Waldauf} and Frits {Prinzen} and Josef {Halámek} and Markéta {Sušánková} and Lucie {Znojilová} and Radovan {Smíšek} and Jakub {Karch} and Filip {Plešinger} and Pawel {Moskal} and Luuk {Heckman} and Jan {Mizner} and Ivo {Viščor} and Vlastimil {Vondra} and Pavel {Leinveber} and Pavel {Osmančík}",
  title="Left Ventricular Myocardial Septal Pacing in Close Proximity to LBB Does Not Prolong the Duration of the Left Ventricular Lateral Wall Depolarization Compared to LBB Pacing",
  journal="Frontiers in Cardiovascular Medicine",
  year="2021",
  volume="8",
  number="1",
  pages="1--10",
  doi="10.3389/fcvm.2021.787414",
  issn="2297-055X",
  url="https://www.frontiersin.org/article/10.3389/fcvm.2021.787414"
}