Publication detail

Binary Phosphorene Redox Behavior in Oxidoreductase Enzymatic Systems

MAYORGA-MARTINEZ, C. SOFER, Z. PUMERA, M.

Original Title

Binary Phosphorene Redox Behavior in Oxidoreductase Enzymatic Systems

Type

journal article in Web of Science

Language

English

Original Abstract

Phosphorene is a two-dimensional material that has many advantageous electronic, electrochemical, and optical properties. However, phosphorene possesses a relatively poor stability in ambient atmosphere. This disadvantage limits its application in several systems and particularly in electrochemical biosensors. Here we evaluate phosphorene as an electrochemical biosensing platform in two different mediator-based oxidoreductase enzymatic systems (glucose oxidase (GOx) and peroxidase from horseradish (HRP)), in which their detection is based on the reduction or oxidation of a mediator. In both cases, the used mediator is the same, ferrocene methanol (FcMeOH). Enhanced electrochemical activity is observed only in the reductive system (HRP-based biosensor) when compared to the oxidative counterpart (GOx-based biosensor). This phenomenon is attributed to the fact that in a reductive environment the phosphorene structure remains intact, while in an oxidative potential, the phosphorene is readily oxidized. In this way, the electroactivity of phosphorene as a sensing platform is strongly dependent on the type of mediator-based enzymatic system. These findings of binary nature of phosphorene are of high importance for construction of phosphorene-sensing platforms and in the development of enzyme logic systems

Keywords

black phosphorus, oxidoreductase enzymes, mediator-based enzymatic biosensor, second-generation biosensor

Authors

MAYORGA-MARTINEZ, C.; SOFER, Z.; PUMERA, M.

Released

17. 10. 2019

ISBN

1936-0851

Periodical

ACS Nano

Year of study

13

Number

11

State

United States of America

Pages from

13217

Pages to

13224

Pages count

8

URL

https://pubs.acs.org/doi/full/10.1021/acsnano.9b06230

BibTex

@article{BUT160763,
  author="Carmen C. {Mayorga-Martinez} and Zdeněk {Sofer} and Martin {Pumera}",
  title="Binary Phosphorene Redox Behavior in Oxidoreductase Enzymatic Systems",
  journal="ACS Nano",
  year="2019",
  volume="13",
  number="11",
  pages="13217--13224",
  doi="10.1021/acsnano.9b06230",
  issn="1936-0851",
  url="https://pubs.acs.org/doi/full/10.1021/acsnano.9b06230"
}