Publication detail

A Thermographic Comparison of Irreversible Electroporation and Radiofrequency Ablation

BERNARD, V. ANDRAŠÍNA, T. ČERVINKA, D. MARTIŠ, J. PROCHÁZKA, P. MORNSTEIN, V. VÁLEK, V.

Original Title

A Thermographic Comparison of Irreversible Electroporation and Radiofrequency Ablation

Type

journal article in Web of Science

Language

English

Original Abstract

Radiofrequency ablation and irreversible electroporation are both interventional procedures used in treating cancer diseases generally and may be used in treatment of liver cancer. The two differ in terms of their action and thermal effects. The present study examined thermal effects of radiofrequency ablation and modified irreversible electroporation ex vivo in porcine liver. Standard radiofrequency ablation was used during the experiments, as was a unique, experimental high-voltage generator of the research team's own construction coupled with a newly designed balloon electrode catheter for irreversible electroporation. The tested balloon catheter was newly designed for application in the biliary tract. The temperature of porcine liver tissue was monitored without contact by infrared camera. The results show significantly different temperature of tissue around electrodes for radiofrequency ablation and irreversible electroporation. The data obtained from radiofrequency ablation with maximum tested output power of 10 watts show a symmetrical area of tissue near active electrodes with temperature increased by more than 30 °C. Irreversible electroporation methods showed temperature increasing approximately by 5 °C. To summarize, the thermal research showed that the difference between standard RFA and innovated IRE with the balloon catheter lies not just in the differing mechanism of action, as is well known, but also in its thermal effects. There was documented that tissue temperature was much higher for RFA than for IRE, particularly for the maximum tested output parameters. The applicability of the newly designed balloon catheters was confirmed.

Keywords

Temperature; Balloon catheter; Heating effect; Infrared camera; Irreversible electroporation; Radiofrequency ablation

Authors

BERNARD, V.; ANDRAŠÍNA, T.; ČERVINKA, D.; MARTIŠ, J.; PROCHÁZKA, P.; MORNSTEIN, V.; VÁLEK, V.

Released

25. 11. 2016

ISBN

1959-0318

Periodical

IRBM

Year of study

38

Number

2

State

French Republic

Pages from

1

Pages to

8

Pages count

8

URL

https://www.sciencedirect.com/science/article/pii/S1959031816300719

BibTex

@article{BUT131070,
  author="Vladan {Bernard} and Tomáš {Andrašína} and Dalibor {Červinka} and Jan {Martiš} and Petr {Procházka} and Vojtěch {Mornstein} and Vlastimil {Válek}",
  title="A Thermographic Comparison of Irreversible Electroporation and Radiofrequency Ablation",
  journal="IRBM",
  year="2016",
  volume="38",
  number="2",
  pages="1--8",
  doi="10.1016/j.irbm.2016.11.001",
  issn="1959-0318",
  url="https://www.sciencedirect.com/science/article/pii/S1959031816300719"
}