Publication result detail

Isolated heart models: cardiovascular system studies and technological advances

OLEJNÍČKOVÁ, V.; NOVÁKOVÁ, M.; PROVAZNÍK, I.

Original Title

Isolated heart models: cardiovascular system studies and technological advances

English Title

Isolated heart models: cardiovascular system studies and technological advances

Type

WoS Article

Original Abstract

Isolated heart model is a relevant tool for cardiovascular system studies. It represents a highly reproducible model for studying broad spectrum of biochemical, physiological, morphological, and pharmaceutical parameters, including analysis of intrinsic heart mechanics, metabolism, and coronary vascular response. Results obtained in this model are under no influence of other organ systems, plasma concentration of hormones or ions and influence of autonomic nervous system. The review describes various isolated heart models, the modes of heart perfusion, and advantages and limitations of various experimental setups. It reports the improvements of perfusion setup according to Langendorff introduced by the authors.

English abstract

Isolated heart model is a relevant tool for cardiovascular system studies. It represents a highly reproducible model for studying broad spectrum of biochemical, physiological, morphological, and pharmaceutical parameters, including analysis of intrinsic heart mechanics, metabolism, and coronary vascular response. Results obtained in this model are under no influence of other organ systems, plasma concentration of hormones or ions and influence of autonomic nervous system. The review describes various isolated heart models, the modes of heart perfusion, and advantages and limitations of various experimental setups. It reports the improvements of perfusion setup according to Langendorff introduced by the authors.

Keywords

Isolated heart; Langendorff; Neely; Monophasic action potential; Electrogram

Key words in English

Isolated heart; Langendorff; Neely; Monophasic action potential; Electrogram

Authors

OLEJNÍČKOVÁ, V.; NOVÁKOVÁ, M.; PROVAZNÍK, I.

RIV year

2016

Released

15.03.2015

Publisher

Springer

ISBN

0140-0118

Periodical

MEDICAL & BIOLOGICAL ENGINEERING & COMPUTING

Volume

2015

Number

3

State

Federal Republic of Germany

Pages from

1

Pages to

9

Pages count

10

URL

http://link.springer.com/article/10.1007/s11517-015-1270-2

BibTex

@article{BUT113338,
  author="Veronika {Olejníčková} and Marie {Nováková} and Valentýna {Provazník}",
  title="Isolated heart models: cardiovascular system studies and technological advances",
  journal="MEDICAL & BIOLOGICAL ENGINEERING & COMPUTING",
  year="2015",
  volume="2015",
  number="3",
  pages="1--9",
  doi="10.1007/s11517-015-1270-2",
  issn="0140-0118",
  url="http://link.springer.com/article/10.1007/s11517-015-1270-2"
}