Publication detail

The COG-or: the Improved Functional Annotation of Bacterial Genomes

POLAKOVIČOVÁ, P. SEDLÁŘ, K.

Original Title

The COG-or: the Improved Functional Annotation of Bacterial Genomes

Type

conference paper

Language

English

Original Abstract

The study of bacterial organisms is given great emphasis in scientific research. By studying the bacterial genome, scientists can gain knowledge of various infectious diseases. Nowadays, it is even possible to edit genes and thus advancing the field of tailored medicine by treating many genetic diseases. Furthermore, it is becoming the norm to utilize bacteria in the industry for their ability to produce important products such as plastics, or fuels. It is therefore essential to extract the necessary information about its genes and other features. This paper focuses mainly on improving the functional annotation of bacterial genomes, classification of protein-coding sequences into clusters of orthologous groups, and visualization of the final annotated genome. For this task, the python package was developed with several functions for working with the outputs of multiple annotation tools, namely eggNOG-mapper, Operon-mapper, and Batch CD-Search. The package was tested on Clostridium diolis DSM 15410 and Clostridium beijerinckii DSM 791.

Keywords

Bacterial genome; Functional annotation; COG; eggNOG-mapper; Operonmapper; Batch CD-Search

Authors

POLAKOVIČOVÁ, P.; SEDLÁŘ, K.

Released

6. 12. 2022

ISBN

978-80-214-6030-0

Book

Proceedings II of the 28st Conference STUDENT EEICT 2022: Selected papers

Pages from

84

Pages to

87

Pages count

4

BibTex

@inproceedings{BUT180303,
  author="Petra {Polakovičová} and Karel {Sedlář}",
  title="The COG-or: the Improved Functional Annotation of Bacterial Genomes",
  booktitle="Proceedings II of the 28st Conference STUDENT EEICT 2022: Selected papers",
  year="2022",
  pages="84--87",
  doi="10.13164/eeict.2022.84",
  isbn="978-80-214-6030-0"
}