Publication detail

Left atrium phasic impairments in paroxysmal atrial fibrillation patients assessed by cardiovascular magnetic resonance feature tracking

LUZ MOJICA-PISCIOTTI, M. PANOVSKÝ, R. MASÁROVÁ, L. PEŠL, M. STÁREK, Z. HOLEČEK, T. FEITOVÁ, V. OPATŘIL, L. DOLEŽALOVÁ, K. KINCL, V.

Original Title

Left atrium phasic impairments in paroxysmal atrial fibrillation patients assessed by cardiovascular magnetic resonance feature tracking

Type

journal article in Web of Science

Language

English

Original Abstract

Atrial fibrillation (AF) is an abnormal and irregular heartbeat caused by uncoordinated electrical impulses in the left atrium (LA), which could induce lasting changes in the heart tissue or could be a consequence of underlying cardiac disease. This study aimed to assess the left atrial phasic function and deformation in paroxysmal AF (PAF) patients-who had not received radiofrequency ablation and had no signs of permanent AF-using the cardiovascular magnetic resonance (CMR) feature-tracking (FT) technique. Fifty subjects (27 PAF patients and 23 controls) were included and examined with CMR. Their LA volume, LA function, LA longitudinal strain (LS) and LA strain rate were assessed in the LA reservoir, conduit, and contractile phases. PAF patients exhibited higher LA volumes than controls, while their LA emptying fraction and LA LS was significantly lower in all three phases. In contrast, the corresponding emptying volumes (total, passive and active) were similar in both groups. The LA volumetric rates from CMR-derived volume curves differed significantly in PAF patients vs controls in the reservoir and contractile phases. In contrast, the equivalent LV volumetric rates were similar. This study suggests that assessing the LA phasic function could offer insight into early LA impairments for PAF patients.

Keywords

HYPERTROPHIC CARDIOMYOPATHY; MYOCARDIAL DEFORMATION; PROGNOSTIC VALUE; STRAIN; VOLUME; QUANTIFICATION; ECHOCARDIOGRAPHY; ASSOCIATION; PHYSIOLOGY; PREDICTOR

Authors

LUZ MOJICA-PISCIOTTI, M.; PANOVSKÝ, R.; MASÁROVÁ, L.; PEŠL, M.; STÁREK, Z.; HOLEČEK, T.; FEITOVÁ, V.; OPATŘIL, L.; DOLEŽALOVÁ, K.; KINCL, V.

Released

9. 5. 2022

Publisher

NATURE PORTFOLIO

Location

BERLIN

ISBN

2045-2322

Periodical

Scientific Reports

Year of study

12

Number

1

State

United Kingdom of Great Britain and Northern Ireland

Pages from

7539

Pages to

7548

Pages count

10

URL

http://nature.com/articles/s41598-022-11233-5

BibTex

@article{BUT178952,
  author="Mary {Luz Mojica-Pisciotti} and Roman {Panovský} and Tomáš {Holeček} and Lucia {Masárová} and Martin {Pešl} and Zdeněk {Stárek} and Věra {Feitová} and Lukáš {Opatřil} and Katarína {Doležalová} and Vladimír {Kincl}",
  title="Left atrium phasic impairments in paroxysmal atrial fibrillation patients assessed by cardiovascular magnetic resonance feature tracking",
  journal="Scientific Reports",
  year="2022",
  volume="12",
  number="1",
  pages="10",
  doi="10.1038/s41598-022-11233-5",
  issn="2045-2322",
  url="http://nature.com/articles/s41598-022-11233-5"
}