Assessment of Magnesium Biodegradability by Micro-CT Platform

Assessment of Magnesium Biodegradability by Micro-CT Platform

Paper in proceedings (conference paper)

Biodegradable metallic materials for medical applications have received considerable attention in recent years. The reason is that they provide high potential for fabrication of temporal orthopaedic implants such as bone fixation devices and scaffolds. Magnesium (Mg) is an excellent candidate for biodegradable implants due to its biocompatibility and relevance for biological body functions. Unfortunately, the high Mg degradation rate limits its application in medicine. Apart from necessity of decrease in corrosion rate of Mg, there is need of a robust, reproducible, accurate technique for quantification of in vitro and in vivo Mg biodegradation and also for evaluation of the effect of various surface treatments, performed to decrease its degradation rate. This research is focused on demonstration of X-ray computed microtomography (μCT) as a non-destructive, quantitative and multianalytical characterization technique to assess the corrosion progress of high-purity-Mg (HP-Mg). The efficacy of the μCT was compared with that of conventional analytical methods which are commonly used for evaluation of Mg degradation.

Biodegradable metallic materials for medical applications have received considerable attention in recent years. The reason is that they provide high potential for fabrication of temporal orthopaedic implants such as bone fixation devices and scaffolds. Magnesium (Mg) is an excellent candidate for biodegradable implants due to its biocompatibility and relevance for biological body functions. Unfortunately, the high Mg degradation rate limits its application in medicine. Apart from necessity of decrease in corrosion rate of Mg, there is need of a robust, reproducible, accurate technique for quantification of in vitro and in vivo Mg biodegradation and also for evaluation of the effect of various surface treatments, performed to decrease its degradation rate. This research is focused on demonstration of X-ray computed microtomography (μCT) as a non-destructive, quantitative and multianalytical characterization technique to assess the corrosion progress of high-purity-Mg (HP-Mg). The efficacy of the μCT was compared with that of conventional analytical methods which are commonly used for evaluation of Mg degradation.

Biodegradable metallic; Magnesium; Degradation; Corrosion; X-ray computed microtomography

Biodegradable metallic; Magnesium; Degradation; Corrosion; X-ray computed microtomography

ROČŇÁKOVÁ, I.; MONTUFAR JIMENEZ, E.; HORYNOVÁ, M.; ZIKMUND, T.; NOVOTNÝ, K.; ČELKO, L.; KLAKURKOVÁ, L.; KAISER, J.

2018

30.08.2015

Polish Society for Biomaterials

Kraków, Poland

978-83-63663-63-6

27th European Conference on Biomaterials - ESB 2015

1000

394

394

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https://eventegg.com/esb-2015-cracow/