Detail publikace

Electrospun biodegradable PCL, PEG and PCL/PEG polyurethane nanofibers coated by amine rich plasma polymers

KEDROŇOVÁ, E., KUPKA, V., MANAKHOV, A., STOICA, A., VOJTOVÁ, L., ZAJÍČKOVÁ, L.

Originální název

Electrospun biodegradable PCL, PEG and PCL/PEG polyurethane nanofibers coated by amine rich plasma polymers

Anglický název

Electrospun biodegradable PCL, PEG and PCL/PEG polyurethane nanofibers coated by amine rich plasma polymers

Jazyk

en

Originální abstrakt

The electrospinning process was employed for the preparation of nanofiber substrates based on hydrophobic poly(caprolactone) (PCL), hydrophilic poly(ethylene glycol) (PEG) and amphiphilic PCL/PEG linear polyurethane (PUR). Thin amine layer by means of the cyclopropylamine plasma polymerization in radio frequency capacitively coupled discharge was deposited on prepared nanofibrous meshes. The possibility for further functionalizing by grafting with chitosan biopolymer through carbodiimide-mediated coupling via citric acid has been tested on a model PCL/PEG PUR foil. Infrared spectroscopy confirmed successful grafting of chitosan onto the PUR surface. Optimizing PUR nanofibers processing can open possible use of the material in wound healing applications exploiting antibacterial properties of chitosan and excellent elasticity, controlled biodegradability and optimal stiffness of PUR.

Anglický abstrakt

The electrospinning process was employed for the preparation of nanofiber substrates based on hydrophobic poly(caprolactone) (PCL), hydrophilic poly(ethylene glycol) (PEG) and amphiphilic PCL/PEG linear polyurethane (PUR). Thin amine layer by means of the cyclopropylamine plasma polymerization in radio frequency capacitively coupled discharge was deposited on prepared nanofibrous meshes. The possibility for further functionalizing by grafting with chitosan biopolymer through carbodiimide-mediated coupling via citric acid has been tested on a model PCL/PEG PUR foil. Infrared spectroscopy confirmed successful grafting of chitosan onto the PUR surface. Optimizing PUR nanofibers processing can open possible use of the material in wound healing applications exploiting antibacterial properties of chitosan and excellent elasticity, controlled biodegradability and optimal stiffness of PUR.

Dokumenty

BibTex


@inproceedings{BUT136071,
  author="Vojtěch {Kupka} and Lucy {Vojtová}",
  title="Electrospun biodegradable PCL, PEG and PCL/PEG polyurethane nanofibers coated by amine rich plasma polymers",
  annote="The electrospinning process was employed for the preparation of nanofiber substrates based on hydrophobic poly(caprolactone) (PCL), hydrophilic poly(ethylene glycol) (PEG) and amphiphilic PCL/PEG linear polyurethane (PUR). Thin amine layer by means of the cyclopropylamine plasma polymerization in radio frequency capacitively coupled discharge was deposited on prepared nanofibrous meshes. The possibility for further functionalizing by grafting with chitosan biopolymer through carbodiimide-mediated coupling via citric acid has been tested on a model PCL/PEG PUR foil. Infrared spectroscopy confirmed successful grafting of chitosan onto the PUR surface. Optimizing PUR nanofibers processing can open possible use of the material in wound healing applications exploiting antibacterial properties of chitosan and excellent elasticity, controlled biodegradability and optimal stiffness of PUR.",
  address="Tanger Ltd.",
  booktitle="NANOCON 2016 - Conference Proceedings",
  chapter="136071",
  edition="1",
  howpublished="print",
  institution="Tanger Ltd.",
  year="2016",
  month="october",
  pages="490--496",
  publisher="Tanger Ltd.",
  type="conference paper"
}