Detail publikace

The Effect of halloysite on structure and properties of polycaprolactone/gelatin nanofibers

ŠVACHOVÁ, V. KHUNOVÁ, V. PAVLIŇÁK, D. FOHLEROVÁ, Z. VOJTOVÁ, L.

Originální název

The Effect of halloysite on structure and properties of polycaprolactone/gelatin nanofibers

Anglický název

The Effect of halloysite on structure and properties of polycaprolactone/gelatin nanofibers

Jazyk

en

Originální abstrakt

The work explores the effects of halloysite nanotubes (HNT) on the structure and properties of ε-polycaprolactone/gelatin (PCL/Gel) nanofibers. Electrospun nanofibers containing 8 wt% Gel and 8 wt% PCL have been prepared by using tissue-friendly solvent—acetic acid. The HNT content in nanofibers has been varied from 0.5 up to 6.0 wt%. The results revealed significant effect of HNT on the obtained nanofiber structure and fiber diameter. Nanofibers with lower HNT concentration provided fibrous structure with HNT particles located predominantly inside the individual fibers. In the case of nanofibers with 6 wt% HNT, the individual particles as well as the agglomerates of HNT have been detected. The highest improvement of mechanical properties (strength—from 1.3 ± 0.1 MPa to 2.2 ± 0.2 MPa and elongation—from 17.5 ± 5.0% to 61.1 ±7.7%) has been achieved when the content of HNT in nanofibers was equal to 0.5 wt%. The addition of HNT also improved the thermal stability and reduced the crystallinity of PCL/Gel nanofibers. The proliferation of NIH-3T3 fibroblasts on PCL/Gel nanofibers was qualitatively observed using fluorescence microscopy. The cells appeared well adhered and characterized by normal fibroblastic behavior on all examined nanofibers.

Anglický abstrakt

The work explores the effects of halloysite nanotubes (HNT) on the structure and properties of ε-polycaprolactone/gelatin (PCL/Gel) nanofibers. Electrospun nanofibers containing 8 wt% Gel and 8 wt% PCL have been prepared by using tissue-friendly solvent—acetic acid. The HNT content in nanofibers has been varied from 0.5 up to 6.0 wt%. The results revealed significant effect of HNT on the obtained nanofiber structure and fiber diameter. Nanofibers with lower HNT concentration provided fibrous structure with HNT particles located predominantly inside the individual fibers. In the case of nanofibers with 6 wt% HNT, the individual particles as well as the agglomerates of HNT have been detected. The highest improvement of mechanical properties (strength—from 1.3 ± 0.1 MPa to 2.2 ± 0.2 MPa and elongation—from 17.5 ± 5.0% to 61.1 ±7.7%) has been achieved when the content of HNT in nanofibers was equal to 0.5 wt%. The addition of HNT also improved the thermal stability and reduced the crystallinity of PCL/Gel nanofibers. The proliferation of NIH-3T3 fibroblasts on PCL/Gel nanofibers was qualitatively observed using fluorescence microscopy. The cells appeared well adhered and characterized by normal fibroblastic behavior on all examined nanofibers.

Dokumenty

BibTex


@article{BUT135352,
  author="Veronika {Pavliňáková} and Viera {Khunová} and David {Pavliňák} and Zdenka {Fohlerová} and Lucy {Vojtová}",
  title="The Effect of halloysite on structure and properties of polycaprolactone/gelatin nanofibers",
  annote="The work explores the effects of halloysite nanotubes (HNT) on the structure and properties of ε-polycaprolactone/gelatin (PCL/Gel) nanofibers. Electrospun nanofibers containing 8 wt% Gel and 8 wt% PCL have been prepared by using tissue-friendly solvent—acetic acid. The HNT content in nanofibers has been varied from 0.5 up to 6.0 wt%. The results revealed significant effect of HNT on the obtained nanofiber structure and fiber diameter. Nanofibers with lower HNT concentration provided fibrous structure with HNT particles located predominantly inside the individual fibers. In the case of nanofibers with 6 wt% HNT, the individual particles as well as the agglomerates of HNT have been detected. The highest improvement of mechanical properties (strength—from 1.3 ± 0.1 MPa to 2.2 ± 0.2 MPa and elongation—from 17.5 ± 5.0% to 61.1 ±7.7%) has been achieved when the content of HNT in nanofibers was equal to 0.5 wt%. The addition of HNT also improved the thermal stability and reduced the crystallinity of PCL/Gel nanofibers. The proliferation of NIH-3T3 fibroblasts on PCL/Gel nanofibers was qualitatively observed using fluorescence microscopy. The cells appeared well adhered and characterized by normal fibroblastic behavior on all examined nanofibers.",
  address="Polymer Engineering and Science",
  chapter="135352",
  doi="10.1002/pen.24512",
  howpublished="online",
  institution="Polymer Engineering and Science",
  number="6",
  volume="57",
  year="2017",
  month="june",
  pages="506--512",
  publisher="Polymer Engineering and Science",
  type="journal article in Web of Science"
}