Detail publikace

Evaluation of handwriting kinematics and pressure for differential diagnosis of Parkinson's disease

DROTÁR, P. MEKYSKA, J. REKTOROVÁ, I. MASÁROVÁ, L. SMÉKAL, Z. FAÚNDEZ ZANUY, M.

Originální název

Evaluation of handwriting kinematics and pressure for differential diagnosis of Parkinson's disease

Typ

článek v časopise ve Web of Science, Jimp

Jazyk

angličtina

Originální abstrakt

We present the PaHaW Parkinson's disease handwriting database, consisting of handwriting samples from Parkinson's disease (PD) patients and healthy controls. Our goal is to show that kinematic features and pressure features in handwriting can be used for the differential diagnosis of PD. The database contains records from 37 PD patients and 38 healthy controls performing eight different handwriting tasks. The tasks include drawing an Archimedean spiral, repetitively writing orthographically simple syllables and words, and writing of a sentence. In addition to the conventional kinematic features related to the dynamics of handwriting, we investigated new pressure features based on the pressure exerted on the writing surface. To discriminate between PD patients and healthy subjects, three different classifiers were compared: K-nearest neighbors (K-NN), ensemble AdaBoost classifier, and support vector machines (SVM). For predicting PD based on kinematic and pressure features of handwriting, the best performing model was SVM with classification accuracy of Pacc = 81.3% (sensitivity Psen = 87.4% and specificity of Pspe = 80.9%). When evaluated separately, pressure features proved to be relevant for PD diagnosis, yielding Pacc = 82.5% compared to Pacc = 75.4% using kinematic features. Experimental results showed that an analysis of kinematic and pressure features during handwriting can help assess subtle characteristics of handwriting and discriminate between PD patients and healthy controls.

Klíčová slova

Decision support system, support vector machine classifier, handwriting database, handwriting pressure, Parkinson's disease, PD dysgraphia

Autoři

DROTÁR, P.; MEKYSKA, J.; REKTOROVÁ, I.; MASÁROVÁ, L.; SMÉKAL, Z.; FAÚNDEZ ZANUY, M.

Vydáno

1. 2. 2016

ISSN

0933-3657

Periodikum

ARTIFICIAL INTELLIGENCE IN MEDICINE

Ročník

67

Číslo

1

Stát

Nizozemsko

Strany od

39

Strany do

46

Strany počet

8

BibTex

@article{BUT123874,
  author="Peter {Drotár} and Jiří {Mekyska} and Irena {Rektorová} and Lucia {Masárová} and Zdeněk {Smékal} and Marcos {Faúndez Zanuy}",
  title="Evaluation of handwriting kinematics and pressure for differential diagnosis of Parkinson's disease",
  journal="ARTIFICIAL INTELLIGENCE IN MEDICINE",
  year="2016",
  volume="67",
  number="1",
  pages="39--46",
  doi="10.1016/j.artmed.2016.01.004",
  issn="0933-3657"
}