Detail publikace

Isolated heart models: cardiovascular system studies and technological advances

OLEJNÍČKOVÁ, V. NOVÁKOVÁ, M. PROVAZNÍK, I.

Originální název

Isolated heart models: cardiovascular system studies and technological advances

Typ

článek v časopise ve Web of Science, Jimp

Jazyk

angličtina

Originální abstrakt

Isolated heart model is a relevant tool for cardiovascular system studies. It represents a highly reproducible model for studying broad spectrum of biochemical, physiological, morphological, and pharmaceutical parameters, including analysis of intrinsic heart mechanics, metabolism, and coronary vascular response. Results obtained in this model are under no influence of other organ systems, plasma concentration of hormones or ions and influence of autonomic nervous system. The review describes various isolated heart models, the modes of heart perfusion, and advantages and limitations of various experimental setups. It reports the improvements of perfusion setup according to Langendorff introduced by the authors.

Klíčová slova

Isolated heart; Langendorff; Neely; Monophasic action potential; Electrogram

Autoři

OLEJNÍČKOVÁ, V.; NOVÁKOVÁ, M.; PROVAZNÍK, I.

Rok RIV

2015

Vydáno

15. 3. 2015

Nakladatel

Springer

ISSN

0140-0118

Periodikum

Medical and Biological Engineering and Computing

Ročník

2015

Číslo

3

Stát

Spolková republika Německo

Strany od

1

Strany do

9

Strany počet

10

URL

http://link.springer.com/article/10.1007/s11517-015-1270-2

BibTex

@article{BUT113338,
  author="Veronika {Olejníčková} and Marie {Nováková} and Valentine {Provazník}",
  title="Isolated heart models: cardiovascular system studies and technological advances",
  journal="Medical and Biological Engineering and Computing",
  year="2015",
  volume="2015",
  number="3",
  pages="1--9",
  doi="10.1007/s11517-015-1270-2",
  issn="0140-0118",
  url="http://link.springer.com/article/10.1007/s11517-015-1270-2"
}