Detail publikačního výsledku

In vitro biocompatibility of differently prepared CMC hydrogels as potential delivery platforms for chronic wound treatment

ROČKOVÁ, V.; SOVKOVÁ, V.; ŽIŽKOVÁ, R.; BRTNÍKOVÁ, J.; VOJTOVÁ, L.; FILOVA, E.

Originální název

In vitro biocompatibility of differently prepared CMC hydrogels as potential delivery platforms for chronic wound treatment

Anglický název

In vitro biocompatibility of differently prepared CMC hydrogels as potential delivery platforms for chronic wound treatment

Druh

Abstrakt

Originální abstrakt

Chronic skin wounds represent a significant healthcare challenge, requiring Advanced therapeutic approaches that can effectively support tissue regeneration while preventing infection. Carboxymethyl cellulose (CMC)-based hydrogels have emerged as promising scaffold materials due to their biocompatibility, easy manipulation, capacity to serve as carriers for therapeutic agents, and properties easily adjusted according to desired outcome. The optimization of CMC gel preparation methods is crucial for developing effective delivery systems that can maintain stability while facilitating the controlled release of bioactive compounds. This study explores ways to study the biocompatibility of differently prepared CMC hydrogels towards key skin cell populations, including fibroblasts (3T3, HDFn) and keratinocytes (HaCaT), investigating their potential as delivery platforms for therapeutic agents in chronic skin wound treatment.

Anglický abstrakt

Chronic skin wounds represent a significant healthcare challenge, requiring Advanced therapeutic approaches that can effectively support tissue regeneration while preventing infection. Carboxymethyl cellulose (CMC)-based hydrogels have emerged as promising scaffold materials due to their biocompatibility, easy manipulation, capacity to serve as carriers for therapeutic agents, and properties easily adjusted according to desired outcome. The optimization of CMC gel preparation methods is crucial for developing effective delivery systems that can maintain stability while facilitating the controlled release of bioactive compounds. This study explores ways to study the biocompatibility of differently prepared CMC hydrogels towards key skin cell populations, including fibroblasts (3T3, HDFn) and keratinocytes (HaCaT), investigating their potential as delivery platforms for therapeutic agents in chronic skin wound treatment.

Klíčová slova

biocompatibility, Carboxymethyl cellulose, polyethyleneglykol, moist healing, hydrogel

Klíčová slova v angličtině

biocompatibility, Carboxymethyl cellulose, polyethyleneglykol, moist healing, hydrogel

Autoři

ROČKOVÁ, V.; SOVKOVÁ, V.; ŽIŽKOVÁ, R.; BRTNÍKOVÁ, J.; VOJTOVÁ, L.; FILOVA, E.

Vydáno

06.05.2025

Místo

Vanajanlinna, Hämeenlinna, Finland

Strany od

31

Strany do

31

Strany počet

64

URL

chrome-extension://efaidnbmnnnibpcajpcglclefindmkaj/https://events.tuni.fi/app/uploads/2025/05/094c07de-scsb-2025-abstracts-poster-presentations.pdf

BibTex

@misc{BUT200681,
  author="{} and  {} and  {} and Jana {Brtníková} and Lucy {Vojtová} and Eva {Filova}",
  title="In vitro biocompatibility of differently prepared CMC hydrogels as potential delivery platforms for chronic wound treatment",
  year="2025",
  pages="31--31",
  address="Vanajanlinna, Hämeenlinna, Finland",
  url="chrome-extension://efaidnbmnnnibpcajpcglclefindmkaj/https://events.tuni.fi/app/uploads/2025/05/094c07de-scsb-2025-abstracts-poster-presentations.pdf",
  note="Abstract"
}