Publication detail

A New Approach how to Define the Coefficient of Electroactivity of Adenine and Its Twelve Derivatives Using Flow Injection Analysis with Amperometric Detection

ZÍTKA, O. ŠKUTKOVÁ, H. ADAM, V. TRNKOVÁ, L. BABULA, P. HUBÁLEK, J. PROVAZNÍK, I. KIZEK, R.

Original Title

A New Approach how to Define the Coefficient of Electroactivity of Adenine and Its Twelve Derivatives Using Flow Injection Analysis with Amperometric Detection

Type

journal article in Web of Science

Language

English

Original Abstract

We studied the electrochemical behaviour of adenine derivates (adenosine, 2 - aminopurine, 2,6 - diaminopurine,6 - benzyl - aminopurine, adenosine - monophosphate, cyclic adenosine monophosphate, nicotin amide adenine dinucleotide, adenosine - triphosphate, S-adenosyl - l - methionine and synthetic derivatives AD -3, AD - 6 and AD-9) using flow injection analysis with electrochemical detection. The influences of pH, flow rate and potential on the signal height of the studied derivates were tested. The optimal pH was 3, the flow rate of the mobile phase 0.75 mL min 1 and the potential 1100 mV. Further, we attempted to characterize each of the studied derivatives by mathematical equations and classic analytical parameters.The lowest detecti on limit was estimated for adenine as 0.9 nM and 2 - amino - purine as 0.5nM

Keywords

Adenine derivatives, Flow injection analysis, Amperometric detection, Glassy carbon electrode, Electroactivity

Authors

ZÍTKA, O.; ŠKUTKOVÁ, H.; ADAM, V.; TRNKOVÁ, L.; BABULA, P.; HUBÁLEK, J.; PROVAZNÍK, I.; KIZEK, R.

RIV year

2011

Released

21. 6. 2011

Publisher

WILEY

Location

Weinheim

ISBN

1040-0397

Periodical

ELECTROANALYSIS

Year of study

23

Number

7

State

Federal Republic of Germany

Pages from

1556

Pages to

1567

Pages count

12

BibTex

@article{BUT50938,
  author="Ondřej {Zítka} and Helena {Vítková} and Vojtěch {Adam} and Libuše {Trnková} and Petr {Babula} and Jaromír {Hubálek} and Valentine {Provazník} and René {Kizek}",
  title="A New Approach how to Define the Coefficient of Electroactivity of Adenine and Its Twelve Derivatives Using Flow Injection Analysis with Amperometric Detection",
  journal="ELECTROANALYSIS",
  year="2011",
  volume="23",
  number="7",
  pages="1556--1567",
  doi="10.1002/elan.201100064",
  issn="1040-0397"
}