Publication detail

Horizontal gene transfer network in chicken gut microbiome

ČEJKOVÁ, D. STREĎANSKÁ, K. JUREČKOVÁ, K. NYKRÝNOVÁ, M. SCHWARZEROVÁ, J. DOLEJSKÁ, M.

Original Title

Horizontal gene transfer network in chicken gut microbiome

English Title

Horizontal gene transfer network in chicken gut microbiome

Type

abstract

Language

en

Original Abstract

Antibiotics have been widely administered as preventive treatment in first days of chicken life in commercial husbandries since newly-hatched chickens are prone to invasive pathogens, especially chicken gut is an outstanding niche for infection. Antibiotic use in farming for decades led also to the selection pressure on chicken commensal bacteria which adapted to those changes by acquisition of antibiotic resistant genes via horizontal gene transfer. Extensive communication between bacteria is characteristic for gut microbiota, thus they are considered reservoirs of antibiotic resistant genes. Therefore, we have identified and characterized key mobile genetic elements such as antibiotic resistance genes and plasmids in chicken gut microbiota using the combination of genomic and cutting-edge metagenomic approaches. In addition, we also have determined which bacterial taxa are predominantly associated with dissemination of mobile genetic elements.

English abstract

Antibiotics have been widely administered as preventive treatment in first days of chicken life in commercial husbandries since newly-hatched chickens are prone to invasive pathogens, especially chicken gut is an outstanding niche for infection. Antibiotic use in farming for decades led also to the selection pressure on chicken commensal bacteria which adapted to those changes by acquisition of antibiotic resistant genes via horizontal gene transfer. Extensive communication between bacteria is characteristic for gut microbiota, thus they are considered reservoirs of antibiotic resistant genes. Therefore, we have identified and characterized key mobile genetic elements such as antibiotic resistance genes and plasmids in chicken gut microbiota using the combination of genomic and cutting-edge metagenomic approaches. In addition, we also have determined which bacterial taxa are predominantly associated with dissemination of mobile genetic elements.

Keywords

Plasmidome, Microbiome, Antibtiotic resistance, Genomics

Released

07.11.2022

Location

Hradec Kralove

ISBN

978-80-906723-2-1

Book

14th Host Pathogen Interaction Forum 2022

Pages count

1

Documents

BibTex 


@misc{BUT180020,
  author="Darina {Čejková} and Katarína {Streďanská} and Kateřina {Jurečková} and Markéta {Nykrýnová} and Jana {Schwarzerová} and Monika {Dolejská}",
  title="Horizontal gene transfer network in chicken gut microbiome",
  annote="Antibiotics have been widely administered as preventive treatment in first days of chicken life in commercial husbandries since newly-hatched chickens are prone to invasive pathogens, especially chicken gut is an outstanding niche for infection. Antibiotic use in farming for decades led also to the selection pressure on chicken commensal bacteria which adapted to those changes by acquisition of antibiotic resistant genes via horizontal gene transfer. Extensive communication between bacteria is characteristic for gut microbiota, thus they are considered reservoirs of antibiotic resistant genes. Therefore, we have identified and characterized key mobile genetic elements such as antibiotic resistance genes and plasmids in chicken gut microbiota using the combination of genomic and cutting-edge metagenomic approaches. In addition, we also have determined which bacterial taxa are predominantly associated with dissemination of mobile genetic elements.",
  booktitle="14th Host Pathogen Interaction Forum 2022",
  chapter="180020",
  year="2022",
  month="november",
  type="abstract"
}