Publication detail

Self-Propelled Tags for Protein Detection

MAYORGA-MARTINEZ, C. PUMERA, M.

Original Title

Self-Propelled Tags for Protein Detection

Type

journal article in Web of Science

Language

English

Original Abstract

Protein detection is of tremendous significance for biological and biomedical sciences. Because there is no equivalent of polymerase chain reaction available as a tool for protein detection, researchers must rely on tags to enhance the limits of detection. One of the crucial steps is the actual labeling of proteins, which relies on diffusion of the label, which is very slow, or external mixing of the label and protein is needed. Here, a conceptually new approach is demonstrated: self-propelled tags that autonomously move in the solution and enhance protein detection. The tags used here are based on IrO2/Pt bilayer microtubules, which can self-propel and act as moving tags for enhanced protein electrochemical detection. This completely new label-based protein detection concept using self-propelled tag will find a wide spectrum of applications.

Keywords

bubble propulsion; hydrogen evolution reaction; label-based protein detection; magneto-immunoassay; micromotor; transitional metal oxides

Authors

MAYORGA-MARTINEZ, C.; PUMERA, M.

Released

1. 2. 2020

Publisher

WILEY-V C H VERLAG GMBH

Location

WEINHEIM

ISBN

1616-301X

Periodical

ADVANCED FUNCTIONAL MATERIALS

Year of study

30

Number

6

State

Federal Republic of Germany

Pages from

1

Pages to

7

Pages count

7

URL

https://onlinelibrary.wiley.com/doi/full/10.1002/adfm.201906449

BibTex

@article{BUT163848,
  author="Carmen C. {Mayorga-Martinez} and Martin {Pumera}",
  title="Self-Propelled Tags for Protein Detection",
  journal="ADVANCED FUNCTIONAL MATERIALS",
  year="2020",
  volume="30",
  number="6",
  pages="1--7",
  doi="10.1002/adfm.201906449",
  issn="1616-301X",
  url="https://onlinelibrary.wiley.com/doi/full/10.1002/adfm.201906449"
}