Publication detail

Effects of Voltage Sensitive Dye di-4-ANEPPS on Guinea Pig Myocardium

Nováková M., Provazník I., Bardoňová J., Blaha M.

Original Title

Effects of Voltage Sensitive Dye di-4-ANEPPS on Guinea Pig Myocardium

Type

conference paper

Language

English

Original Abstract

Voltage-sensitive dyes have been employed to record monophasic action potentials (MAPs) in a variety of heart preparations with results comparable to classical microelectrode method. However, still little data are available on the response of the heart muscle to the loading with the dye. One of the most consistently used dyes – di-4-ANEPPS - is employed in our laboratory to record MAPs from isolated guinea pig hearts. It is of great importance to prove that loading of the heart muscle does not result in pharmacological or toxic effects to the preparation, since the experiments are of long duration, e.g. to prove the viability and quality of the heart at the beginning of the experiment.

Keywords

Voltage-sensitive dye, monophasic action potential, heart, di-4-ANEPPS

Authors

Nováková M., Provazník I., Bardoňová J., Blaha M.

RIV year

2005

Released

5. 9. 2005

Publisher

IFBME

Location

Praha

ISBN

0-7803-8894-1

Book

Proceedings of EMBEC 2005

Pages from

1

Pages to

1

Pages count

1

BibTex

@inproceedings{BUT14703,
  author="Marie {Nováková} and Valentine {Provazník} and Jana {Kolářová} and Milan {Blaha}",
  title="Effects of Voltage Sensitive Dye di-4-ANEPPS on Guinea Pig Myocardium",
  booktitle="Proceedings of EMBEC 2005",
  year="2005",
  pages="1",
  publisher="IFBME",
  address="Praha",
  isbn="0-7803-8894-1"
}