Novel nanoelectrode system for extracellular potential measurement of cells

conference paper

English

In-vivo impedance measurements of cells are the objective of current scientific research in area of biological sciences. A problem that needs to be solved is how to measure extracellular potential without causing trauma or damage in living cells. One possible solution is based on nanoelectrodes that are fabricated due to current high technology level. The main goal of this work is to design and create nanoelectrode with pair of gold nanowires using standard thin-film techniques (micro- and nanotechniques) and special ion- and electron beam methods. New dual electrode system is designed for long term potential measurements in water based culture medium for single cell. The novel nanoelectrode pair is realized on a silicon wafer. In order to avoid oxidation of nanoelectrodes for material is choosen gold. Main part of novel system is fabricated with lithography technics and FIB etching. The pair of gold nanowires is growed with pulsed electrochemical methods. The size of nanowires is ideal for measurements without interactions between electrodes and a single cell.

lithography, nano electrodes, focused ion beam, electrochemistry

MÁRIK, M.; SVATOŠ, V.; PEKÁREK, J.; CHOMOUCKÁ, J.; HUBÁLEK, J.

2013

16. 10. 2013

Tanger, Ltd.

Ostrava

978-80-87294-47-5

Conference Proceedings 5th International Conference NANOCON 2013

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